44 Results for "

Anti-hyperglycemic activity

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "Anti-hyperglycemic activity" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-14291
CAS No.: 274901-16-5
Purity:  99.93%
Synonyms: LAF237; NVP-LAF 237
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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5
5 Cited Publications
Cat. No.: HY-N1390
CAS No.: 134-96-3
Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .
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4
4 Cited Publications
Cat. No.: HY-N0669
CAS No.: 57817-89-7
Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities .
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3
3 Cited Publications
Cat. No.: HY-N0472
CAS No.: 60976-49-0
Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, and anti-hyperglycemic activities, with an IC50 of 43 μM.
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1
1 Cited Publications
Cat. No.: HY-N2168
CAS No.: 69251-96-3
Synonyms: (+)-Pinoresinol 4-O-β-D-glucopyranoside
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is an orally active α-glucosidase inhibitor, with an IC50 of 48.13 μg/mL. Pinoresinol 4-O-β-D-glucopyranoside binds to estrogen receptors. Pinoresinol 4-O-β-D-glucopyranoside inhibits phosphodiesterase. Pinoresinol 4-O-β-D-glucopyranoside exhibits various activities such as antioxidant, anti-inflammatory, anti-hyperglycemic, hepatoprotective and anti-epileptic effects .
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Cat. No.: HY-109500
CAS No.: 27686-84-6
Purity:  99.76%
Synonyms: meso-Nordihydroguaiaretic acid; meso-NDGA
Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes .
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Cat. No.: HY-N7133
CAS No.: 537-67-7
Synonyms: N-Phenylaniline hydrochloride
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent .
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Cat. No.: HY-131488
CAS No.: 23532-11-8
Purity:  99.81%
8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity .
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Cat. No.: HY-110118
CAS No.: 213411-83-7
Purity:  99.58%
Target:  

PPAR

Research Areas:  

Metabolic Disease

Edaglitazone is a potent, selective and orally active PPARγ agonist, with EC50s of 35.6 nM and 1053 nM for PPARα and PPARγ, respectively. Edaglitazone displays antiplatelet, antidiabetic and anti-hyperglycemic activity .
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Cat. No.: HY-W068771
CAS No.: 943-89-5
(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities .
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Cat. No.: HY-133127
CAS No.: 1065609-00-8
Purity:  99.84%
Target:  

Glucokinase

Research Areas:  

Metabolic Disease

AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity .
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Cat. No.: HY-N1185
CAS No.: 59979-61-2
Tagitinin A is a sesquiterpene with anti-hyperglycemic activity. Tagitinin A significantly inhibits glucose uptake in differentiated 3T3-L1 adipocytes .
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Cat. No.: HY-A0176
CAS No.: 25046-79-1
Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect .
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Cat. No.: HY-N0336A
CAS No.: 72917-31-8
Synonyms: (Z)-Butylidenephthalide
(Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC50=2.35 mM; Ki=4.86 mM) .
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Cat. No.: HY-N0669R
CAS No.: 57817-89-7
Stevioside (Standard) is the analytical standard of Stevioside. This product is intended for research and analytical applications. Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities .
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Cat. No.: HY-N3078
CAS No.: 84873-15-4
p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic (yeast α-glucosidase, IC50=19.24 ± 1.73 µM), antioxidant, and anti-inflammatory activities . p-Hydroxyphenethyl trans-ferulate shows inhibiting anticancer and serotonergic activity .
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Cat. No.: HY-178935
CAS No.: 1099611-82-1
α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an α-amylase inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes .
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Cat. No.: HY-14291A
CAS No.: 2133364-01-7
Synonyms: LAF237 dihydrate; NVP-LAF 237 dihydrate
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability and potent antihyperglycemic activity .
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Cat. No.: HY-14291S1
CAS No.: 1133208-42-0
Synonyms: LAF237-d7; NVP-LAF 237-d7
Vildagliptin-d7 is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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Cat. No.: HY-14291S
CAS No.: 1217546-82-1
Synonyms: LAF237-d3; NVP-LAF 237-d3
Vildagliptin-d3 is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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