1. Glisoxepide

Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect.

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Glisoxepide Chemical Structure

Glisoxepide Chemical Structure

CAS No. : 25046-79-1

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Description

Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect[1][2][3].

IC50 & Target

K(ATP) channel[1]

In Vitro

Glisoxepide inhibits the uptake of bile acids into isolated rat hepatocytes[3].
Glisoxepide noncompetitively inhibits the cholate uptake with a Ki of 200 μM[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

449.52

Formula

C20H27N5O5S

CAS No.
SMILES

O=C(C1=NOC(C)=C1)NCCC2=CC=C(S(=O)(NC(NN3CCCCCC3)=O)=O)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glisoxepide
Cat. No.:
HY-A0176
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