1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Glisoxepide

Glisoxepide 

Cat. No.: HY-A0176
Handling Instructions

Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect.

For research use only. We do not sell to patients.

Glisoxepide Chemical Structure

Glisoxepide Chemical Structure

CAS No. : 25046-79-1

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Description

Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect[1][2][3].

IC50 & Target

K(ATP) channel[1]

In Vitro

Glisoxepide inhibits the uptake of bile acids into isolated rat hepatocytes[3].
Glisoxepide noncompetitively inhibits the cholate uptake with a Ki of 200 μM[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

449.52

Formula

C20H27N5O5S

CAS No.
SMILES

O=C(C1=NOC(C)=C1)NCCC2=CC=C(S(=O)(NC(NN3CCCCCC3)=O)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Glisoxepide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glisoxepide
Cat. No.:
HY-A0176
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