Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
BAY-k 5552-d6
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "BAY-k 5552-d6" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: (±)-BAY K 8644
Target:
Research Areas:
Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca 2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca 2+ influx through sarcolemmal Ca 2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .
9
9 Cited Publications
Target:
Research Areas:
(S)-(-)-Bay-K-8644 is an agonist of L-type Ca 2+ channel. (S)-(-)-Bay-K-8644 activates Ba 2+ currents (IBa) (EC50=32 nM).
2
Research Areas:
Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity .
2
2 Cited Publications
Target:
Research Areas:
(R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba 2+ currents (IBa) (IC50=975 nM).
Cat. No.: HY-17402R
CAS No.: 63675-72-9
Synonyms: BAY-k 5552 (Standard)
Research Areas:
Nisoldipine (Standard) is the analytical standard of Nisoldipine. This product is intended for research and analytical applications. Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM.
Cat. No.: HY-17402S3
CAS No.: 1432057-47-0
Synonyms: BAY-k 5552-d3
Cat. No.: HY-17402S
CAS No.: 1285910-03-3
Synonyms: BAY-k 5552-d6
Cat. No.: HY-10588R
CAS No.: 71145-03-4
Synonyms: (±)-BAY K 8644 (Standard)
Target:
Research Areas:
Bay K 8644 (Standard) is the analytical standard of Bay K 8644. This product is intended for research and analytical applications. Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .
Cat. No.: HY-P5552
CAS No.: 709611-59-6
Melimine is an antimicrobial peptide with broad-spectrum antimicrobial activity against Gram-negative/Gram-positive bacteria, fungi and protozoa. Melimine neutralizes endotoxin activity by interacting with the phosphate groups of lipid A, depolarizes and permeabilizes the cytoplasmic membrane of *Pseudomonas aeruginosa*, and induces bacterial lysis. Melimine exerts additive antiviral effects against H1N1 and MHV-1 when used in combination with RK610. Melimine retains its antimicrobial activity when conjugated to polymer and titanium surfaces. Melimine can be used in infection-related research .
Target:
Research Areas:
Prenylamine lactate is a calcium-modulating protein (CaM) antagonist that inhibits CaM-dependent enzymes and can slowly relax smooth muscle preparations. The effect of Prenylamine lactate on smooth muscle is not inhibited by the calcium agonist Bay K 8644 (HY-10588). Reports suggest that under low heart rate conditions, Prenylamine seems to enhance voltage-dependent transmembrane calcium currents .
Cat. No.: HY-17402S1
CAS No.: 1219795-47-7
Cat. No.: HY-17402S2
CAS No.: 1189718-34-0
Cat. No.: HY-A0257AR
CAS No.: 69-43-2
Target:
Research Areas:
Prenylamine (lactate) (Standard) is the analytical standard of Prenylamine (lactate). This product is intended for research and analytical applications. Prenylamine lactate is a calcium-modulating protein (CaM) antagonist that inhibits CaM-dependent enzymes and can slowly relax smooth muscle preparations. The effect of Prenylamine lactate on smooth muscle is not inhibited by the calcium agonist Bay K 8644 (HY-10588). Reports suggest that under low heart rate conditions, Prenylamine seems to enhance voltage-dependent transmembrane calcium currents .
Cat. No.: HY-N6776R
CAS No.: 12627-35-9
Category:
Target:
Cat. No.: HY-P5552A
Melimine acetate is an antimicrobial peptide with broad-spectrum antimicrobial activity against Gram-negative/Gram-positive bacteria, fungi and protozoa. Melimine acetate neutralizes endotoxin activity by interacting with the phosphate groups of lipid A, depolarizes and permeabilizes the cytoplasmic membrane of *Pseudomonas aeruginosa*, and induces bacterial lysis. Melimine acetate exerts additive antiviral effects against H1N1 and MHV-1 when used in combination with RK610. Melimine acetate retains its antimicrobial activity when conjugated to polymer and titanium surfaces. Melimine acetate can be used in infection-related research .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
