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Results for "

CETP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CETP (21) Apolipoprotein (3) Cannabinoid Receptor (1) Drug Intermediate (2) HMG-CoA Reductase (HMGCR) (1) LDLR (3) LPL Receptor (3) MHC (1) PCSK9 (2) PPAR (1) Reference Standards (4) Small Interfering RNA (siRNA) (1) Thrombin (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (15) Endocrinology (1) Inflammation/Immunology (2) Metabolic Disease (9)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Natural
Products

Antibodies

Oligonucleotides

Targets Recommended: CETP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13327

Evacetrapib 3 Publications Verification LY2484595	CETP	Cardiovascular Disease
Evacetrapib is a potent and selective of *CETP* inhibitor, which inhibits human recombinant CETP protein (IC₅₀ 5.5 nM) and CETP activity in human plasma (IC₅₀ 36 nM) in vitro.

HY-18778

Obicetrapib TA-8995; DEZ-001; AMG-899	CETP Apolipoprotein LPL Receptor LDLR	Cardiovascular Disease
Obicetrapib (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .

HY-12090

Anacetrapib 3 Publications Verification MK-0859	PCSK9	Cardiovascular Disease
Anacetrapib is a potent *CETP* inhibitor, with IC₅₀s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively.

HY-12089

Torcetrapib CP-529414	CETP	Endocrinology
Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .

HY-14950

Dalcetrapib 2 Publications Verification JTT-705; RO4607381	CETP	Cardiovascular Disease Cancer
Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC₅₀s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .

HY-W414588

Colestolone	HMG-CoA Reductase (HMGCR) CETP	Metabolic Disease
Colestolone is a 15-ketosterol compound and an orally active inhibitor of HMG-CoA reductase. Colestolone can inhibit the activity of cholesteryl ester transfer protein (CETP) in vitro (IC₅₀= 660 μM). Colestolone is a cholesterol-lowering agent, and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia .

HY-116078

CKD-519	CETP	Cardiovascular Disease
CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC₅₀ of 2.3 nM .

HY-W015752

5-Methoxyresorcinol	Drug Intermediate	Others
5-Methoxyresorcinol is a model molecule of the A ring of flavonoids, specifically simulating the chemical behavior of the resorcinol-type A ring found in catechins. 5-Methoxyresorcinol exhibits extremely low reactivity of tocopherol. 5-Methoxyresorcinol hardly inhibits cholesteryl ester transfer protein (CETP) .

HY-171883

BI-5756	Cannabinoid Receptor CETP MHC	Metabolic Disease Inflammation/Immunology Cancer
BI-5756 is a *CETP* inhibitor and cannabinoid receptor 1 (CB1) agonist. BI-5756 can significantly increase HDL-C levels and reduce LDL-C levels. BI-5756 can also enhance the function of regulatory T cells while maintaining T cell-mediated anti-tumor activity. BI-5756 can directly inhibit the growth of tumor cells and upregulate the expression of MHC I, MHC II, and CD80 on tumor cells. BI-5756 has a protective effect in graft-versus-host disease models. BI-5756 can be used in research on tumors, graft-versus-host disease, and metabolic diseases .

HY-19614

BMS-795311	CETP	Cardiovascular Disease
BMS-795311 is a potent and orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP), with IC₅₀s of 4 nM in an enzyme-based scintillation proximity assay (SPA) and 0.22 μM in a human whole plasma assay (hWPA), respectively .

HY-107997

TAP311	CETP	Cardiovascular Disease
TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC₅₀ of 62 nM .

HY-123039

CP-532623	CETP	Metabolic Disease
CP-532623 is a *CETP* inhibitor and elevates high-density lipoprotein cholesterolion. CP-532623 is a close structural analogue of Torcetrapib. CP-532623 has highly lipophilic properties .

HY-105316

CP-800569	CETP	Metabolic Disease
CP-800569 is an orally active cholesteryl ester transfer protein (CETP) inhibitor. CP-800569 can decrease low-density lipoprotein and postprandial triglyceride and increase high-density lipoprotein. CP-800569 can be used for the research of metabolic disease .

HY-142643

CETP-IN-4	CETP	Metabolic Disease
CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor.

HY-128338

CETP-IN-3	CETP	Cardiovascular Disease
CETP-IN-3 (Compound 13) is an small molecule inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP. CETP-IN-3 for the CETP inhibitory activity in the scintillation proximity (SPA) and whole plasma assay (WPA) with IC₅₀s of 0.002 μM and 0.06 μM, respectively .

HY-107054

ESP-31015 ETC-1001	PPAR	Cardiovascular Disease
ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research .

HY-RS02549

CETP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CETP Human Pre-designed siRNA Set A contains three designed siRNAs for CETP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CETP Human Pre-designed siRNA Set A CETP Human Pre-designed siRNA Set A

HY-13327R

Evacetrapib (Standard) LY2484595 (Standard)	CETP Reference Standards	Cardiovascular Disease
Evacetrapib (Standard) is the analytical standard of Evacetrapib. This product is intended for research and analytical applications. Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.

HY-14950R

Dalcetrapib (Standard) JTT-705 (Standard); RO4607381 (Standard)	CETP Reference Standards	Cardiovascular Disease Cancer
Dalcetrapib (Standard) is the analytical standard of Dalcetrapib. This product is intended for research and analytical applications. Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .

HY-12090R

Anacetrapib (Standard) MK-0859 (Standard)	PCSK9 Reference Standards	Cardiovascular Disease
Anacetrapib (Standard) is the analytical standard of Anacetrapib. This product is intended for research and analytical applications. Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively.

HY-169723

CP 524515	CETP	Metabolic Disease
CP 524515 is a potent inhbitor of cholesteryl ester transfer protein (CETP) that leads to elevated high-density lipoprotein cholesterol levels .

HY-123550

Rosenonolactone	Thrombin CETP	Inflammation/Immunology
Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin and cholesterol ester transfer protein .

HY-132303

MK-8262	CETP	Cardiovascular Disease Metabolic Disease
MK-8262 is an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor with an IC₅₀ of 53 nM and a log D of 5.3. MK-8262, a bistrifluoromethyl analogue, has the potential for coronary heart disease (CHD) correlated high-density lipoprotein (HDL) and low-density lipoprotein (LDL) research .

HY-W015752R

5-Methoxyresorcinol (Standard)	Reference Standards Drug Intermediate	Others
5-Methoxyresorcinol (Standard) is an analytical standard for 5-Methoxyresorcinol (HY-W015752). This product is intended for research and analytical applications. 5-Methoxyresorcinol is a model molecule for the A ring of flavonoids, specifically mimicking the chemical behavior of the resorcinol-type A ring in catechins. 5-Methoxyresorcinol exhibits very low tocopherol regeneration activity. 5-Methoxyresorcinol shows little inhibition of cholesteryl ester transfer protein (CETP).

HY-18778B

Obicetrapib potassium TA-8995 potassium; DEZ-001 potassium; AMG-899 potassium	Apolipoprotein CETP LPL Receptor LDLR	Metabolic Disease
Obicetrapib (TA-8995; DEZ-001) potassium is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potassium potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib potassium can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .

HY-N8353

Stachybotramide	Others	Metabolic Disease
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL .

HY-18778A

Obicetrapib sodium TA-8995 sodium; DEZ-001 sodium; AMG-899 sodium	Apolipoprotein CETP LPL Receptor LDLR	Cardiovascular Disease
Obicetrapib (TA-8995; DEZ-001) sodium is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib sodium potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib sodium can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .

HY-182320

DRL-17822	CETP	Cardiovascular Disease
DRL-17822 is a selective cholesteryl ester transfer protein (CETP) inhibitor. DRL-17822 increases high-density lipoprotein levels. The exposure of DRL-17822 nanocrystal formulation increases significantly after a high-fat breakfast. The exposure of DRL-17822 in the fasted state is higher than that of its nanocrystal formulation. DRL-17822 can be used in the research of type II hyperlipidemia and atherosclerotic cardiovascular disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015752

5-Methoxyresorcinol	Classification of Application Fields Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate
5-Methoxyresorcinol is a model molecule of the A ring of flavonoids, specifically simulating the chemical behavior of the resorcinol-type A ring found in catechins. 5-Methoxyresorcinol exhibits extremely low reactivity of tocopherol. 5-Methoxyresorcinol hardly inhibits cholesteryl ester transfer protein (CETP) .

HY-123550

Rosenonolactone	Microorganisms Terpenoids Diterpenoids Source Classification	Thrombin CETP
Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin and cholesterol ester transfer protein .

HY-W015752R

5-Methoxyresorcinol (Standard)	Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Drug Intermediate
5-Methoxyresorcinol (Standard) is an analytical standard for 5-Methoxyresorcinol (HY-W015752). This product is intended for research and analytical applications. 5-Methoxyresorcinol is a model molecule for the A ring of flavonoids, specifically mimicking the chemical behavior of the resorcinol-type A ring in catechins. 5-Methoxyresorcinol exhibits very low tocopherol regeneration activity. 5-Methoxyresorcinol shows little inhibition of cholesteryl ester transfer protein (CETP).

HY-N8353

Stachybotramide	Natural Products Microorganisms Source Classification	Others
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (1) Mouse (1)
Application:	IHC-P (1) IP (1) WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83236

	CETP Antibody (YA2981) BPIFF; HDLCQ10; CETP; Lipid transfer protein I; Cholesteryl ester transfer protein	WB, IP	Human
	CETP Antibody (YA2981) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CETP.

HY-P810357

	CETP Antibody (YA9679) BPIFF, CETP, CETP_HUMAN, Cholesteryl ester transfer protein, Cholesteryl ester transfer protein plasma, HDLCQ10, Lipid transfer protein I	WB, IHC-P	Human, Mouse, Rat
	CETP Antibody (YA9679) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to CETP.

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CETP Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CETP Human Pre-designed siRNA Set A contains three designed siRNAs for CETP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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