875446-37-0
875446-37-0
Chemical Structure
Anacetrapib
Synonym(s): MK-0859
- CAS No.: 875446-37-0
- Formula:C30H25F10NO3
- Molecular Weight:637.51
IUPAC Name: (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methyl)-4-methyloxazolidin-2-one
InChIKey: MZZLGJHLQGUVPN-HAWMADMCSA-N
SMILES: O=C1O[C@@H]([C@@H](N1CC2=CC(C(F)(F)F)=CC=C2C3=CC(C(C)C)=C(C=C3OC)F)C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4
Biological Activity: Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Anacetrapib | 99.25% | Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively. | ||||||||||||||||||||
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Anacetrapib (Standard) | ≥98% | Anacetrapib (Standard) is the analytical standard of Anacetrapib. This product is intended for research and analytical applications. Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.65
HY-116078CKD-519 -
Similarity Score 0.57
HY-132303MK-8262 -
Similarity Score 0.51
HY-142643CETP-IN-4 -
Similarity Score 0.46
HY-13213AM211 -
Similarity Score 0.46
HY-13213AAM211 sodium -
Similarity Score 0.43
HY-16436Rolapitant hydrochloride hydrate -
Similarity Score 0.43
HY-12140Vestipitant -
Similarity Score 0.43
HY-14751ARolapitant hydrochloride -
Similarity Score 0.42
HY-14751Rolapitant -
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