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Art. -Nr.: HY-107054

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ESP-31015

Name: ESP-31015
Brand: MedChemExpress
SKU: HY-107054
Availability: PreOrder

(Synonyms: ETC-1001)

ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 413624-55-2
Formel: C₁₇H₃₄O₃
Molecular Weight:286.45

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

ESP-31015 Chemical Structure

CAS. Nr.: 413624-55-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

PPARα

Alle PPAR Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Hepatocyte	IC₅₀	1.5 μM Compound: 39	Inhibition of lipid synthesis in primary rat hepatocytes by incorporation radiolabeled acetate into cellular lipids Inhibition of lipid synthesis in primary rat hepatocytes by incorporation radiolabeled acetate into cellular lipids	[PMID: 16392818]
Hepatocyte	IC₅₀	4 μM Compound: 14c	Concentration required for inhibition of lipid synthesis in primary cultures of rat hepatocytes Concentration required for inhibition of lipid synthesis in primary cultures of rat hepatocytes	[PMID: 15537362]

In Vivo

ESP-31015 (100 mg/kg, p.o., once daily for 2 weeks) shows a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides in female obese Zucker fatty rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Female obese Zucker fatty rats model^[1]
Dosage:

100 mg/kg
Administration:

Oral administration (p.o.), once daily for 2 weeks
Result:

Showed a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides.

Chemical Information

CAS. Nr. 413624-55-2
Molecular Weight 286.45
Formel C₁₇H₃₄O₃
SMILES

OCC(C)(C)CCCCC(CCCCC(C)(C)CO)=O
Synonyms

ETC-1001
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Pal M, et al. HDL elevators and mimetics--emerging therapies for atherosclerosis. Cardiovasc Hematol Agents Med Chem. 2007 Jan;5(1):55-66. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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