1 Result for "

CNS-compartmentalized B-cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CNS-compartmentalized B-cells" in MCE Product Catalog:

Cat. No.: HY-182943
BTK-IN-49 is a selective, orally active and brain-penetrant BTK inhibitor with an IC50 of 0.14 nM. BTK-IN-49 binds to BTK and blocks B-cell receptor and Fcγ receptor signaling. BTK-IN-49 inhibits the proliferation of CNS-compartmentalized B-cells and FcγR-induced microglial proliferation in a BTK-dependent manner. BTK-IN-49 can be used for the study of multiple sclerosis .
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