7 Results for "

CaM-dependent phosphodiesterase

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "CaM-dependent phosphodiesterase" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-103319
CAS No.: 57265-65-3
Purity:  99.94%
Synonyms: R 24571
Target:  

Autophagy Calmodulin

Research Areas:  

Neurological Disease Cancer

Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively . Also in anti-cancer research . Calmidazolium binds to calmodulin with a Kd of 3 nM.
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3
3 Cited Publications
Cat. No.: HY-P1077
CAS No.: 145224-99-3
CALP1 is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca 2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity .
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3
3 Cited Publications
Cat. No.: HY-P1077A
CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca 2+-binding site. CALP1 TFA blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 TFA blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 TFA activates CaM-dependent phosphodiesterase activity .
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Cat. No.: HY-P1076A
Target:  

Calmodulin

Research Areas:  

Inflammation/Immunology

CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca 2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca 2+ concentrations. CALP2 TFA potently inhibits of adhesion and degranulation. CALP2 TFA is also a strong activator of alveolar macrophages .
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Cat. No.: HY-P1076
CAS No.: 261969-04-4
Target:  

Calmodulin

Research Areas:  

Inflammation/Immunology

CALP2 is a calmodulin (CaM) antagonist ( (Kd of 7.9 µM)) with high affinity for binding to the CaM EF-hand/Ca 2+-binding site. CALP2 inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca 2+ concentrations. CALP2 potently inhibits of adhesion and degranulation. CALP2 is also a strong activator of alveolar macrophages .
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Cat. No.: HY-103319R
CAS No.: 57265-65-3
Synonyms: R 24571 (Standard)
Calmidazolium chloride (Standard) is the analytical standard of Calmidazolium chloride (HY-103319). This product is intended for research and analytical applications. Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively . Also in anti-cancer research . Calmidazolium binds to calmodulin with a Kd of 3 nM.
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Cat. No.: HY-N21792
CAS No.: 213842-42-3
4-Hydroxy-3,3',5-trimethoxybibenzyl is a synthetic bibenzyl analog with spasmolytic activity. It inhibits spontaneous contractions of isolated guinea pig ileum. In the presence of Ca 2+, 4-Hydroxy-3,3',5-trimethoxybibenzyl also alters the electrophoretic mobility of bovine brain calmodulin (calmodulin), supporting its interaction with CaM. It can be used in studies of smooth muscle contraction and calmodulin-related processes .
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