197 Results for "

Chromogenic Substrate

" in MedChemExpress (MCE) Product Catalog:
Products (197)

197 Results for "Chromogenic Substrate" in MCE Product Catalog:

194
Thiazolyl Blue
Thiazolyl Blue
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194 Publications Verification
Cat. No.: HY-15924
CAS No.: 298-93-1
Synonyms: MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
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142
D-Luciferin sodium
D-Luciferin sodium
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142 Cited Publications
Cat. No.: HY-12591
CAS No.: 103404-75-7
Purity:  99.92%
Synonyms: D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
D-luciferin sodium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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142
D-Luciferin
D-Luciferin
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142 Cited Publications
Cat. No.: HY-12591A
CAS No.: 2591-17-5
Purity:  99.54%
Synonyms: D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
Category:  

Natural Products Animals Other Diseases Disease Research Fields

Target:  

Fluorescent Dye

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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142
D-Luciferin potassium
D-Luciferin potassium
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142 Cited Publications
Cat. No.: HY-12591B
CAS No.: 115144-35-9
Purity:  99.97%
Synonyms: D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
D-luciferin potassium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
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17
WST-8
WST-8
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17 Cited Publications
Cat. No.: HY-D0831
CAS No.: 193149-74-5
WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay.
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14
ABTS diammonium salt
ABTS diammonium salt
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14 Cited Publications
Cat. No.: HY-15902
CAS No.: 30931-67-0
Purity:  99.86%
Synonyms: AzBTS-(NH4)2
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .
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11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Caesalpinia sappan L. Other Diseases Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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11
Z-Gly-Gly-Arg-AMC
Z-Gly-Gly-Arg-AMC
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11 Cited Publications
Cat. No.: HY-P0019
CAS No.: 66216-78-2
Target:  

Fluorescent Dye Thrombin

Research Areas:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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11
Z-Gly-Gly-Arg-AMC acetate
Z-Gly-Gly-Arg-AMC acetate
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11 Cited Publications
Cat. No.: HY-P0019A
CAS No.: 2070009-61-7
Target:  

Fluorescent Dye Thrombin

Research Areas:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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8
TMB
TMB
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8 Cited Publications
Cat. No.: HY-15930
CAS No.: 54827-17-7
Synonyms: BM blue; Sure Blue TMB
TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
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8
TMB dihydrochloride
TMB dihydrochloride
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8 Cited Publications
Cat. No.: HY-15930A
CAS No.: 64285-73-0
Synonyms: BM blue dihydrochloride; Sure Blue TMB dihydrochloride
TMB dihydrochloride is the dihydrochloride form of TMB (HY-15930). TMB dihydrochloride is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB dihydrochloride can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB dihydrochloride can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
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8
TMB monosulfate
TMB monosulfate
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8 Cited Publications
Cat. No.: HY-15930C
CAS No.: 54827-18-8
Synonyms: BM blue monosulfate; Sure Blue TMB monosulfate
TMB monosulfate is the monosulfate form of TMB (HY-15930). TMB monosulfate is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB monosulfate can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB monosulfate can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
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7
Fluorescein di(β-D-galactopyranoside)
Fluorescein di(β-D-galactopyranoside)
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7 Cited Publications
Cat. No.: HY-101895
CAS No.: 17817-20-8
Purity:  99.81%
Synonyms: FDG
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm).
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7
AkaLumine hydrochloride
AkaLumine hydrochloride
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7 Cited Publications
Cat. No.: HY-112641A
CAS No.: 2558205-28-8
Purity:  99.92%
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
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7
Nitro blue tetrazolium chloride
Nitro blue tetrazolium chloride
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7 Cited Publications
Cat. No.: HY-15925
CAS No.: 298-83-9
Synonyms: NBT
Target:  

Fluorescent Dye

Research Areas:  

Others

Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
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6
X-GAL
X-GAL
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6 Cited Publications
Cat. No.: HY-15934
CAS No.: 7240-90-6
Synonyms: BCIG
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
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5
Ac-DEVD-AMC
Ac-DEVD-AMC
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5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
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4
Z-Gly-Pro-AMC
Z-Gly-Pro-AMC
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4 Cited Publications
Cat. No.: HY-D1670
CAS No.: 68542-93-8
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm) .
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3
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
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3 Cited Publications
Cat. No.: HY-W010991
CAS No.: 64967-39-1
Synonyms: FAPGG
Target:  

Angiotensin-converting Enzyme (ACE)

Research Areas:  

Others

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10 -4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system .
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3
CycLuc1
CycLuc1
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3 Cited Publications
Cat. No.: HY-111653
CAS No.: 1247879-16-8
Purity:  99.72%
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
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