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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
CycT1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "CycT1" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: BAY-1143572
Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb/CDK9 inhibitor. Atuveciclib (BAY-1143572) inhibits CDK9/CycT1 with an IC50 of 13 nM [1].
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1 Cited Publications
Synonyms: BAY-1143572 Racemate
Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib. Atuveciclib is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
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Synonyms: BAY-1143572 S-Enantiomer; (+)-Atuveciclib; (+)-BAY-1143572
Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is a potent and selective CDK9 inhibitor, which inhibits CDK9/CycT1 with an IC50 of 16 nM.
Cat. No.: HY-156795
CAS No.: 3020773-91-2
Target:
Research Areas:
CDK9/CycT1 degrader-1 is an autophagy-anchored bifunctional degrader that mediates the degradation of the CDK9/cyclin T1 protein complex. CDK9/CycT1 degrader-1 binds both CDK9 and LC3B simultaneously to form a ternary complex, achieving target protein degradation via the autophagy-lysosome pathway. CDK9/CycT1 degrader-1 downregulates the protein levels of Mcl‑1 and c‑Myc and induces apoptosis. PROTAC CDK9/CycT1 Degrader-2 is applicable to cancer-related research [1].
Cat. No.: HY-E70676
CDK20 is a major controller of cell cycle checkpoints, which regulate cell growth and proliferation and perform a role in the development of many malignancies. CDK20 is thought to have Cyclin-dependent activating kinase (CAK) activity for CDK2 when it is complexed with Cyclin H. CDK20/CycT1 Recombinant Human Active Protein Kinase is an ortholog of CDK20 [1].
Cat. No.: HY-13231R
CAS No.: 1415559-43-1
CDK9-IN-1 (Standard) is the analytical standard of CDK9-IN-1. This product is intended for research and analytical applications. CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.
Cat. No.: HY-P703098
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCNT1; Cyclin-T1; Prev. HIVE1; Cyclin C-Related Protein; CycT1; MLLT10/CCNT1 Fusion; CCNT; Cyclin-T; Human Immunodeficiency Virus Type 1 (HIV-1) Expression (Elevated) 1; CycT1; Cyclin T1; CDK9-Associated C-Type Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-RS17636
Target:
Research Areas:
Cyc1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cyc1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180187
019854-B06 is a potent inhibitor of Tat-mediated HIV-1 transcription (IC50 = 1.44 μM), exhibiting antiviral activity against HIV-1 (EC50 = 0.83 μM). 019854-B06 binds to Tat peptide (KD = 33.5 μM), but not to TAR RNA. 019854-B06 neither promotes Tat degradation nor disrupts the Tat/CycT1 complex, supporting a Tat-centric, nondegradative mechanism [1].
Cat. No.: HY-RS21506
Target:
Research Areas:
Ccnt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccnt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02141
Target:
Research Areas:
CCNT1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701376
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated Kinase Complex Catalytic Subunit; Prev. CDC2L4; Cyclin-Dependent Kinase 9 (CDC2-Related Kinase); TAK; Serine/Threonine Protein Kinase PITALRE; Cell Division Protein Kinase 9; Serine/Threonine-Protein Kinase PITALRE; Cyclin-Dependent K
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
