1. Cell Cycle/DNA Damage
    Anti-infection
  2. CDK
    HIV
  3. CDK9-IN-1

CDK9-IN-1 

Cat. No.: HY-13231 Purity: 95.48%
Handling Instructions

CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.

For research use only. We do not sell to patients.

CDK9-IN-1 Chemical Structure

CDK9-IN-1 Chemical Structure

CAS No. : 1415559-43-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 108 In-stock
Estimated Time of Arrival: December 31
5 mg USD 98 In-stock
Estimated Time of Arrival: December 31
10 mg USD 185 In-stock
Estimated Time of Arrival: December 31
50 mg USD 528 In-stock
Estimated Time of Arrival: December 31
100 mg USD 960 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection, with an IC50 of 39 nM for CDK9/CycT1, extracted from reference, compound 87.

IC50 & Target

CDK9/CycT1

39 nM (IC50)

In Vitro

CDK9-IN-1 is a potent CDK9 inhibitor that shows high activity against HIV-1 replication[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

499.54

Formula

C₂₆H₂₁N₅O₄S

CAS No.

1415559-43-1

SMILES

CC1=C(NS(C)(=O)=O)C=C(NC2=NC=NC(C3=CC=CC(N4C(C5=C(C=CC=C5)C4=O)=O)=C3)=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (50.05 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0018 mL 10.0092 mL 20.0184 mL
5 mM 0.4004 mL 2.0018 mL 4.0037 mL
10 mM 0.2002 mL 1.0009 mL 2.0018 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CDK9-IN-1CDKHIVCyclin dependent kinaseHuman immunodeficiency virusInhibitorinhibitorinhibit

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Product Name:
CDK9-IN-1
Cat. No.:
HY-13231
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