6 Results for "

Cyclic GMP-AMP (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Cyclic GMP-AMP (Standard)" in MCE Product Catalog:

Cyclic GMP (Standard)
Cyclic GMP (Standard)
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Cat. No.: HY-113469R
CAS No.: 7665-99-8
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

Cyclic GMP (Standard) is the analytical standard of Cyclic GMP (HY-113469). This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
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2',3'-cGAMP sodium (Standard)
2',3'-cGAMP sodium (Standard)
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Cat. No.: HY-100564AR
CAS No.: 2734858-36-5
Synonyms: 2'-3'-Cyclic GMP-AMP sodium (Standard)
Category:  

Natural Products Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite STING IFNAR

2',3'-cGAMP sodium (Standard) is the analytical standard of 2',3'-cGAMP sodium (HY-100564A). This product is intended for research and analytical applications. 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm .
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2',3'-cGAMP (Standard)
2',3'-cGAMP (Standard)
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Cat. No.: HY-100564R
CAS No.: 1441190-66-4
Synonyms: 2'-3'-Cyclic GMP-AMP (Standard)
Category:  

Natural Products Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite STING IFNAR

2',3'-cGAMP (Standard) is the analytical standard of 2',3'-cGAMP (HY-100564). This product is intended for research and analytical applications. 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .
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cGAMP (Standard)
cGAMP (Standard)
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Cat. No.: HY-12512R
CAS No.: 849214-04-6
Synonyms: Cyclic GMP-AMP (Standard); 3',3'-cGAMP (Standard)
Target:  

Reference Standards STING

Research Areas:  

Inflammation/Immunology

cGAMP (Standard) is the analytical standard of cGAMP (HY-12512). This product is intended for research and analytical applications. cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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Cyclic GMP sodium (Standard)
Cyclic GMP sodium (Standard)
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Cat. No.: HY-113469AR
CAS No.: 40732-48-7
Category:  

Natural Products Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Cyclic GMP sodium (Standard) is the analytical standard of Cyclic GMP sodium (HY-113469A). This product is intended for research and analytical applications. Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
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RU.521 (Standard)
RU.521 (Standard)
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Cat. No.: HY-114180R
CAS No.: 2262452-06-0
Synonyms: RU320521 (Standard)
Target:  

Reference Standards Cyclic GMP-AMP Synthase

Research Areas:  

Metabolic Disease

RU.521 (Standard) is the analytical standard of RU.521 (HY-114180). This product is intended for research and analytical applications. RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) .
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