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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
DNA binding subunit
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "DNA binding subunit" in MCE Product Catalog:
37
37 Publications Verification
Target:
SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .
6
Category:
other families Terpenoids Sesquiterpenes Plants Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
IT-901 is an orally active and potent NF-κB subunit c-Rel inhibitor with an IC50 of 0.1 μM, 3 μM for NF-κB DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD) .
1
1 Cited Publications
Cat. No.: HY-P80936
Synonyms: YBX1; NSEP1; YB1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-
Cat. No.: HY-W017834
CAS No.: 38336-04-8
Synonyms: 2-(Benzyloxy)ethylamine
Target:
Research Areas:
2-(Benzyloxy)-1-ethanamine (2-(Benzyloxy) ethylamine) is a biochemical reagent that can be used as a biological material or organic compound for life science-related research .
Cat. No.: HY-N11739
CAS No.: 53658-84-7
Target:
Cat. No.: HY-P71135
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NFYA; CAAT-Box DNA binding Protein subunit A; Nuclear Transcription Factor Y subunit Alpha; CAAT Box DNA-binding Protein subunit A; NF-YA; Nuclear Transcription Factor Y subunit; CBF-B; Transcription Factor NF-Y, A subunit; HAP2; HAP2 CCAAT-binding Protei
Species:
Human
Source:
E. coli
Cat. No.: HY-P80737
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
Cat. No.: HY-P85251
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
Cat. No.: HY-P85582
Synonyms: Damage specific DNA binding protein 1; Damage-specific DNA-binding protein 1; DDB 1; DDB p127 subunit; Ddb1; DDB1_HUMAN; DDBa; DNA damage binding protein 1; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1; UV damaged DNA binding factor; UV damaged DNA binding protein 1; UV DDB 1; UV DDB1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; X associated protein 1; XAP 1; XAP-1; XAP1; Xeroderma pigmentosum group E complementing protein; Xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE BF; XPE binding factor; XPE-BF; XPE-binding factor.
Cat. No.: HY-P80737A
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
Cat. No.: HY-P71124
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NFKB1; KBF1; Nuclear Factor Kappa B subunit 1; P105; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1; P50; Nuclear Factor NF-Kappa-B P105 subunit; Nuclear Factor Kappa-B DNA binding subunit; DNA-binding Factor KBF1; Nuclear Factor NF-
Species:
Human
Source:
E. coli
Cat. No.: HY-189124
Target:
Research Areas:
Antibacterial agent 372 is a potent antibacterial agent. Antibacterial agent 372 is a DNA gyrase inhibitor that binds to the ATP-binding pocket of the GyrB subunit, downregulates gyrB gene expression, and impedes DNA replication and supercoiling. Antibacterial agent 372 exhibits broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Antibacterial agent 372 can be used for research on microbial infections .
Cat. No.: HY-P80375
Synonyms: NSEP1, YB1, YBX1, Y-box-binding protein 1, YB-1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, CBF-A, DBPB, EFI-A
Cat. No.: HY-P87886
Synonyms: NSEP1, YB1, YBX1, Y-box-binding protein 1, YB-1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, CBF-A, DBPB, EFI-A
Cat. No.: HY-P703562
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: WDTC1; WD And Tetratricopeptide Repeats Protein 1; WD And Tetratricopeptide Repeats 1; DDB1 And CUL4 Associated Factor 9; KIAA1037; Adipose Homolog (Drosophila); DCAF9; Adipose Homolog; ADP; DDB1; XPE-BF; Damage Specific DNA binding Protein 1; XAP-1; DNA Damage-binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-Complementing Protein; Damage-Specific DNA binding Protein 1 (127kD); Damage-Specific DNA-binding Protein 1; Damage-Specific DNA binding Protein 1, 127kDa; UV-Damaged DNA-binding Protein 1; UV-DDB1; UV-Damaged DNA-binding Factor; WHIKERS; DNA Damage-binding Protein A; DDBA; HBV X-Associated Protein 1; XPCE; XPE-binding Factor; XPCe; DDB P127 subunit; DDBa; UV-DDB 1; XPE
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703363
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCAF10; WD Repeat-Containing Protein 32; Prev. WDR32; MGC10765; DDB1- And CUL4-Associated Factor 10; FLJ23201; DDB1 And CUL4 Associated Factor 10; WD Repeat Domain 32; DDB1; XPE-BF; Damage Specific DNA binding Protein 1; XAP-1; DNA Damage-binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-Complementing Protein; Damage-Specific DNA binding Protein 1 (127kD); Damage-Specific DNA-binding Protein 1; Damage-Specific DNA binding Protein 1, 127kDa; UV-Damaged DNA-binding Protein 1; UV-DDB1; UV-Damaged DNA-binding Factor; WHIKERS; DNA Damage-binding Protein A; DDBA; HBV X-Associated Protein 1; XPCE; XPE-binding Factor; XPCe; DDB P127 subunit; DDBa; UV-DDB 1; XPE
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
