Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
FP receptor agonist
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "FP receptor agonist" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: Prostaglandin F2α; PGF2α
10
10 Publications Verification
Synonyms: Prostaglandin F2α tromethamine salt; PGF2α THAM; Prostaglandin F2α THAM
5
Target:
Research Areas:
Latanoprost (PHXA41) is a prostaglandin F2α analogue and can be used for glaucoma research. Latanoprost can effectively pass through cornea and be hydrolyzed by esterase to latanoprost acid. latanoprost acid is an F-prostaglandin (FP) receptor agonist, and can effectively reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor through uvea .
3
3 Cited Publications
Cat. No.: HY-B0584
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester; AL6221; Flu-Ipr
Target:
Research Areas:
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
1
Research Areas:
Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma .
1
1 Cited Publications
Target:
Research Areas:
Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .
Synonyms: DE-117
Target:
Research Areas:
Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration, and Omidenepag is a highly selective EP2 receptor agonist. Omidenepag isopropyl shows only weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropyl is under development for the treatment of glaucoma as an intraocular pressure (IOP)-lowering agent.
Cat. No.: HY-12956S
CAS No.: 34210-11-2
Synonyms: Prostaglandin F2a-d4; PGF2α-d4
Cat. No.: HY-125774
CAS No.: 38344-08-0
Synonyms: 17-Phenyl trinor PGF2α
Target:
Research Areas:
Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .
Target:
Research Areas:
17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
Cat. No.: HY-B0584R
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)
Research Areas:
Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Cat. No.: HY-113246
CAS No.: 35850-13-6
Synonyms: 15-keto-PGF2α
Cat. No.: HY-156101
CAS No.: 919281-21-3
Target:
Research Areas:
Latanoprost amide is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost (HY-B0577) .
Cat. No.: HY-159704
CAS No.: 141074-06-8
Target:
Research Areas:
9-keto latanoprost is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost (HY-B0577) .
Cat. No.: HY-139121
CAS No.: 41639-71-8
Synonyms: 15-epi Bimatoprost free acid; 15(R)-Bimatoprost free acid; 15(R)-17-phenyl trinor PGF2α
Target:
Research Areas:
15(R)-17-Phenyl trinor Prostaglandin F2α (15-epi Bimatoprost free acid) is a prostaglandin F (FP) analog that acts as an ocular hypotensive agent. The free acid 17-Phenyl trinor Prostaglandin F2α is a potent FP receptor agonist. 15(R)-17-Phenyl trinor Prostaglandin F2α is the 15-epi or "unnatural" isomer of this active free acid metabolite and has reduced FP receptor agonist activity.
Cat. No.: HY-100571
CAS No.: 157283-66-4
Target:
Research Areas:
Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM .
Cat. No.: HY-176017
Target:
Research Areas:
2,3-Dinor fluprostenol is a derivative of the FP receptor agonist and prostaglandin F2α (PGF2α) analog fluprostenol (HY-136494) .
Cat. No.: HY-120982
CAS No.: 54276-22-1
Target:
Research Areas:
Cloprostenol is a synthetic prostaglandin F2α (PGF2α) analog and a potent FP receptor agonist. (+)-15-epi Cloprostenol is the 15(S), or 15β-hydroxy enantiomer of (+)-cloprostenol. This epimer is less active by several orders of magnitude as an FP receptor ligand when compared to 15(R)-cloprostenol. However, the specific activity of this isomer has not been well studied.
Cat. No.: HY-116549
CAS No.: 13261-27-3
Synonyms: PGF2α alcohol
Target:
Research Areas:
Prostaglandin F2α alcohol (PGF2α alcohol) is an analog of PGF2α. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
