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Results for "

Fibroblast growth factor receptor 3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FGFR (5) Apoptosis (1) Caspase (1) mRNA (1) PROTACs (1) TNK1 (1)
By Research Areas:	Cancer (4)
Oligonucleotides:	mRNA (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Oligonucleotides

Targets Recommended: FGFR FAP GHR VEGFR TGF-β Receptor PDGFR EGFR IGF-1R GHSR TGF-beta/Smad Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3503

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (*natriuretic peptide receptor* type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3**). Vosoritide can be used in achondroplasia and dwarfism research .

HY-P99823

Recifercept TA-46; sFGFR3	FGFR	Others
Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .

HY-174688

Human FGFR3 mRNA	mRNA	Cancer
Human FGFR3 mRNA encodes the human fibroblast growth factor receptor 3 (FGFR3) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR3 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

HY-181153

PROTAC FGFR3 Degrader-1	PROTACs FGFR	Cancer
PROTAC FGFR3 Degrader-1 is a fibroblast growth factor receptor 3 (FGFR3) PROTAC degrader, promotes FGFR3 degradation via the ubiquitin-proteasome pathway, and inhibits the downstream FGFR3/PI3K/AKT signaling pathway. PROTAC FGFR3 Degrader-1 can be used for the research of hepatocellular carcinoma .

HY-181152

FGFR3-IN-11	FGFR	Cancer
FGFR3-IN-11(compound B11) is a Fibroblast growth factor receptor 3 (FGFR3) inhibitor with a K_a value of 4.8 μM. FGFR3-IN-11 induces apoptosis, suppresses colony formation, and causes dose-dependent G0/G1 cell cycle arrest in cancer cells. FGFR3-IN-11 exerts anticancer activity against cancer cells with minimal toxicity toward normal hepatocytes and demonstrates tumor growth suppression in xenograft mouse models. FGFR3-IN-11 can be used for the research of hepatocellular carcinoma .

HY-181752

FGFR3-IN-12	FGFR TNK1 Apoptosis Caspase	Cancer
FGFR3-IN-12 is a selective fibroblast growth factor receptor 3 (FGFR3) inhibitor with an IC₅₀ of 6.8 nM. FGFR3-IN-12 shows an IC₅₀ of 19.2 nM against FGFR3 ^V555Mand an IC₅₀ of 16.9 nM against TNK1 (Thirty-eight Negative Kinase 1). FGFR3-IN-12 inhibits cancer cells proliferation and induces caspase-mediated apoptosis. FGFR3-IN-12 exhibits antitumor activity in bladder cancer xenografts mice models. FGFR3-IN-12 can be used for the research of cancer, such as bladder cancer .

Cat. No.	Product Name	Target	Research Area

HY-P3503

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (*natriuretic peptide receptor* type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3**). Vosoritide can be used in achondroplasia and dwarfism research .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99823

Recifercept TA-46; sFGFR3	FGFR	Others
Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .

Species:	Human (12) Rhesus Macaque (1) Mouse (2) Cynomolgus (1)
Tag:	His (14) Strep (1) GST (7) B2M (1) Fc (3)
Source:	HEK293 (6) sf9 insect cells (3) P. pastoris (1) Sf9 insect cells (5) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P706050

	FGFR-3 Protein, Human (Active, sf9, His-GST) Fibroblast growth factor receptor 3; JTK4	Human	Sf9 insect cells

HY-P73056

	FGFR-3 Protein, Mouse (HEK293, His-Fc) Fibroblast growth factor receptor 3; FGFR-3; CD333; JTK4	Mouse	HEK293
	The FGFR-3 Protein is a member of the fibroblast growth factor receptor family. FGFR-3 Protein regulates chondrocyte differentiation and chondrocyte proliferation by activating the MAPK/STAT signaling pathway. FGFR-3 mutations are also associated with sperm cell tumors. FGFR-3 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived FGFR-3 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P702760

	FGFR-3 Protein, Human (sf9, His, Strep) Fibroblast growth factor receptor 3; FGFR-3; CD333; JTK4	Human	Sf9 insect cells
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (sf9, His, Flag) is the recombinant human-derived FGFR-3, expressed by Sf9 insect cells, with His, Flag labeled tag. The total length of FGFR-3 Protein, Human (sf9, His, Flag) is 311 a.a..

HY-P706051

	FGFR-3 Protein, Human (Active, G697C, sf9, His-GST) Fibroblast growth factor receptor 3; JTK4	Human	Sf9 insect cells

HY-P706052

	FGFR-3 Protein, Human (Active, N540K, sf9, His-GST) Fibroblast growth factor receptor 3; JTK4	Human	Sf9 insect cells

HY-P706053

	FGFR-3 Protein, Human (Active, V555L, sf9, His-GST) Fibroblast growth factor receptor 3; JTK4	Human	Sf9 insect cells

HY-P72644

	FGFR-3 alpha (IIIc) Protein, Human (HEK293, His) Fibroblast growth factor receptor 3; FGFR-3; CD333; JTK4	Human	HEK293
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIc) Protein, Human (HEK293, His) is the recombinant human-derived FGFR-3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74153

	FGFR-3 Protein, Mouse (HEK293, His) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Mouse	HEK293
	The FGFR-3 protein is a tyrosine protein kinase that serves as a cell surface receptor for fibroblast growth factors and controls cellular processes, including proliferation, differentiation, and apoptosis. It is essential for chondrocyte differentiation, proliferation, apoptosis and normal bone development functions. FGFR-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGFR-3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700484

	FGFR-3 Protein, Human (P. pastoris, N-His) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Human	P. pastoris
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (P. pastoris, N-His) is the recombinant human-derived FGFR-3 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P76342

	FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Rhesus Macaque	HEK293
	FGFR-3 is a member of the fibroblast growth factor receptor family and is expressed in tissues such as cartilage, brain, intestine and kidney. FGFR-3 regulates chondrocyte differentiation and proliferation by activating the MAPK/STAT signaling pathway. FGFR-3 is a tumor marker. FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant cynomolgus-derived FGFR-3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76341

	FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Cynomolgus	HEK293
	FGFR-3 is a member of the fibroblast growth factor receptor family and is expressed in tissues such as cartilage, brain, intestine and kidney. FGFR-3 regulates chondrocyte differentiation and proliferation by activating the MAPK/STAT signaling pathway. FGFR-3 is a tumor marker. FGFR-3 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant cynomolgus-derived FGFR-3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70817

	FGFR-3 alpha (IIIc) Protein, Human (HEK293, Fc) 1 Publications Verification Fibroblast growth factor receptor 3; FGFR-3; CD333; FGFR3; JTK4; IIIc	Human	HEK293
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIc) Protein, Human (HEK293, Fc) is the recombinant human-derived FGFR-3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P705833

	FGFR-3 Protein, Human (Active, V555M, sf9, His-GST) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Human	sf9 insect cells

HY-P705834

	FGFR-3 Protein, Human (Active, K650M, sf9, His-GST) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Human	sf9 insect cells

HY-P705835

	FGFR-3 Protein, Human (Active, K650E, sf9, His-GST) Fibroblast growth factor receptor 3; FGFR-3; CD333; Mfr3; Sam3	Human	sf9 insect cells

HY-P72196

	FGFR-3 Protein, Human (His-B2M) ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3	Human	E. coli
	The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 Protein, Human (His-B2M) is the recombinant human-derived FGFR-3 protein, expressed by E. coli , with N-6*His, N-B2M labeled tag.

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Cat. No.	Product Name		Classification

HY-174688

Human FGFR3 mRNA		mRNA
Human FGFR3 mRNA encodes the human fibroblast growth factor receptor 3 (FGFR3) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR3 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

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