2 Results for "

Foxp3+CD4+ regulatory T cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Foxp3+CD4+ regulatory T cells" in MCE Product Catalog:

Cat. No.: HY-W060417
CAS No.: 1019158-02-1
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease .
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Cat. No.: HY-P992005

Research Areas:  

Cancer

DS-1055a is an anti-human GARP antibody. DS-1055a effectively depletes GARP-positive regulatory T cells in the tumor microenvironment, and activates effector T cells. DS-1055a exhibits antitumor activity and can be used for the research of cancer, such as colon cancer .
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