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Results for "

G-protein α subunit

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

2

Natural
Products

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013706
    Inosine-5'-triphosphate trisodium salt

    ITP trisodium salt; Inosine triphosphate trisodium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt
  • HY-P5985
    mSIRK
    2 Publications Verification

    		 ERK Others
    mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange .
    mSIRK
  • HY-171978A
    LM-189 free base

    		Adrenergic Receptor Cardiovascular Disease
    LM-189 free base, a G protein alpha subunit I (Gαi)-biased agonist, is a Gαi-biased ligand of β2-adrenergic receptor (β2AR). LM-189 free base stabilizes a distinct conformation in TM6 and increases the dynamics of ICL2. LM-189 free base can be used to develop the Gαi-biased β2AR agonists .
    LM-189 free base
  • HY-W686762
    m,p-Dimethyl PPE

    		Dopamine Receptor Adenylate Cyclase Neurological Disease
    m,p-Dimethyl PPE is a D4 dopamine receptor ligand. m,p-Dimethyl PPE promotes GDP/GTP exchange of the G protein α-subunit, dissociates the receptor-G protein complex, stabilizes the low-affinity receptor state, and inhibits adenylate cyclase activity. m,p-Dimethyl PPE inhibits Forskolin (HY-15371)-induced melatonin synthesis in retinal photoreceptor cells and reduces the efficacy of full agonists when used in combination. m,p-Dimethyl PPE can be used in studies related to attention-deficit hyperactivity disorder .
    m,p-Dimethyl PPE
  • HY-150172A
    Inosine 5'-triphosphate lithium salt

    ITP lithium salt; Inosine triphosphate lithium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
    Inosine 5'-triphosphate lithium salt
  • HY-W013706R
    Inosine-5'-triphosphate trisodium salt (Standard)

    ITP trisodium salt (Standard); Inosine triphosphate trisodium salt (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    Inosine-5'-triphosphate (trisodium salt) (Standard) is the analytical standard of Inosine-5'-triphosphate (trisodium salt) (HY-W013706). This product is intended for research and analytical applications. Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt (Standard)

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