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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
GABA-transaminase
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "GABA-transaminase" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: γ-Vinyl-GABA
Target:
Research Areas:
Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .
6
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
6
6 Publications Verification
Cat. No.: HY-B0033
CAS No.: 1391054-02-6
Synonyms: γ-Vinyl-GABA hydrochloride
Target:
Research Areas:
Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .
2
2 Cited Publications
Synonyms: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
Category:
Microorganisms Neurological Disease Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics Cancer
Target:
2
2 Cited Publications
Synonyms: L-2,4-Diaminobutyric acid
Category:
Neurological Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer
Target:
2
2 Cited Publications
Synonyms: L-2,4-Diaminobutyric acid hydrobromide
Category:
Neurological Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer
Target:
1
1 Cited Publications
Cat. No.: HY-W012738
CAS No.: 149-87-1
Target:
Research Areas:
DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action .
Synonyms: GAG hydrochloride
Target:
Research Areas:
γ-Acetylenic GABA (GAG) hydrochloride is an irreversible inhibitor of GABA-transaminase. γ-Acetylenic GABA hydrochloride can increase the concentration of GABA in rat brain . γ-Acetylenic GABA (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-N15001
CAS No.: 59556-18-2
Category:
Target:
Cat. No.: HY-116910
CAS No.: 640897-20-7
Target:
Research Areas:
CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms .
Cat. No.: HY-B1018AS
CAS No.: 1219798-40-9
Cat. No.: HY-131693
CAS No.: 57659-38-8
Synonyms: GAG
Target:
Research Areas:
γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is an irreversible inhibitor of GABA-transaminase. γ-Acetylenic GABA can increase the concentration of GABA in rat brain . γ-Acetylenic GABA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-B0033S
Synonyms: γ-Vinyl-GABA-13C,d2 hydrochloride
Cat. No.: HY-15399R
CAS No.: 68506-86-5
Synonyms: γ-Vinyl-GABA (Standard)
Target:
Research Areas:
Vigabatrin (Standard) is the analytical standard of Vigabatrin. This product is intended for research and analytical applications. Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .
Cat. No.: HY-W778008
CAS No.: 1330171-61-3
Cat. No.: HY-101414R
CAS No.: 1758-80-1
Synonyms: L-2,4-Diaminobutyric acid (Standard)
Synonyms: (S)-Cycloserine (Standard); (S)-4-Amino-3-isoxazolidone (Standard)
Target:
Cat. No.: HY-P82219A
Synonyms: ABAT; GABA transaminase; GABA transferase; GABAT; LAIBAT
Cat. No.: HY-B0033R
CAS No.: 1391054-02-6
Synonyms: γ-Vinyl-GABA hydrochloride (Standard)
Target:
Research Areas:
Vigabatrin (hydrochloride) (Standard) is the analytical standard of Vigabatrin (hydrochloride). This product is intended for research and analytical applications. Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
