L-Cycloserine (Standard)
L-Cycloserine (Standard) is the analytical standard of L-Cycloserine. This product is intended for research and analytical applications. L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains[1][2][3][4].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98%
- CAS 番号: 339-72-0
- 分子式: C3H6N2O2
- 分子量:102.09
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
-
CAS 番号 339-72-0
-
分子量 102.09
-
分子式 C3H6N2O2
-
SMILES
O=C1NOC[C@@H]1N
-
別名
(S)-Cycloserine (Standard); (S)-4-Amino-3-isoxazolidone (Standard)
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Tathyana Mar Amorim Franco, et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem Biol. 2017 May 19;12(5):1235-1244. [Content Brief]
[2]. S H Chung, et al. L-cycloserine: a potent anticonvulsant. Epilepsia. 1984 Jun;25(3):353-62. [Content Brief]
[3]. P Polc, et al. L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats. Neuropharmacology. 1986 Apr;25(4):411-8. [Content Brief]
[4]. K S Sundaram, et al. Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. J Lipid Res. 1985 Apr;26(4):473-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- L-Cycloserine (Standard)
- 339-72-0
- (S)-Cycloserine (Standard)
- (S)-4-Amino-3-isoxazolidone (Standard)
- Reference Standards
- GABA Receptor
- HIV
- Brain cerebroside synthesis
- anticonvulsant
- Mycobacterium tuberculosis branched-chain aminotransferase
- gamma-aminobutyric acid (GABA)-aminotransferase
- Inhibitor
- inhibitor
- inhibit