L-Cycloserine (Standard)
L-Cycloserine (Standard) is the analytical standard of L-Cycloserine. This product is intended for research and analytical applications. L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains[1][2][3][4].
For research use only. We do not sell to patients.
- CAS No.: 339-72-0
- Formula: C3H6N2O2
- Molecular Weight:102.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 339-72-0
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Molecular Weight 102.09
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Formula C3H6N2O2
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SMILES
O=C1NOC[C@@H]1N
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Synonyms
(S)-Cycloserine (Standard); (S)-4-Amino-3-isoxazolidone (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tathyana Mar Amorim Franco, et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem Biol. 2017 May 19;12(5):1235-1244. [Content Brief]
[2]. S H Chung, et al. L-cycloserine: a potent anticonvulsant. Epilepsia. 1984 Jun;25(3):353-62. [Content Brief]
[3]. P Polc, et al. L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats. Neuropharmacology. 1986 Apr;25(4):411-8. [Content Brief]
[4]. K S Sundaram, et al. Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. J Lipid Res. 1985 Apr;26(4):473-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- L-Cycloserine (Standard)
- 339-72-0
- (S)-Cycloserine (Standard)
- (S)-4-Amino-3-isoxazolidone (Standard)
- Reference Standards
- GABA Receptor
- HIV
- Brain cerebroside synthesis
- anticonvulsant
- Mycobacterium tuberculosis branched-chain aminotransferase
- gamma-aminobutyric acid (GABA)-aminotransferase
- Inhibitor
- inhibitor
- inhibit