339-72-0
339-72-0
Chemical Structure
L-Cycloserine
Synonym(s): (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
- CAS No.: 339-72-0
- Formula:C3H6N2O2
- Molecular Weight:102.09
IUPAC Name: (S)-4-aminoisoxazolidin-3-one
InChIKey: DYDCUQKUCUHJBH-REOHCLBHSA-N
SMILES: O=C1NOC[C@@H]1N
Biological Activity: L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Cycloserine | 98.84% | L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains. | ||||||||||||||||||||
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L-Cycloserine (Standard) | ≥98% | L-Cycloserine (Standard) is the analytical standard of L-Cycloserine. This product is intended for research and analytical applications. L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-B0030D-Cycloserine -
Similarity Score 1.00
HY-W008440DL-Cycloserine -
Similarity Score 0.75
HY-W580812(R)-3-Aminopyrrolidine-2,5-dione -
Similarity Score 0.75
HY-W580836(S)-3-Aminopyrrolidine-2,5-dione -
Similarity Score 0.71
HY-210883-Amino-2-piperidinone -
Similarity Score 0.71
HY-W003592R(S)-3-Aminopiperidin-2-one (Standard) -
Similarity Score 0.71
HY-W141589(R)-3-Aminopiperidin-2-one -
Similarity Score 0.70
HY-W003592AL-Orinithine lactam hydrochloride -
Similarity Score 0.70
HY-100822(R)-(+)-HA-966 -
Explore the MedChemAI to find more analogs
References
- [1]. Tathyana Mar Amorim Franco, et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem Biol. 2017 May 19;12(5):1235-1244. [Content Brief]
- [2]. S H Chung, et al. L-cycloserine: a potent anticonvulsant. Epilepsia. 1984 Jun;25(3):353-62. [Content Brief]
- [3]. P Polc, et al. L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats. Neuropharmacology. 1986 Apr;25(4):411-8. [Content Brief]
- [4]. K S Sundaram, et al. Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. J Lipid Res. 1985 Apr;26(4):473-7. [Content Brief]
