2 Results for "

HIV-infected CD4 T cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HIV-infected CD4 T cells" in MCE Product Catalog:

Cat. No.: HY-P991479
CAS No.: 2839531-84-7
Synonyms: GS-8588

Target:  

HIV CD3

Research Areas:  

Infection

Amtabafusp alfa (GS-8588) is an envelope-targeting bispecific T-cell engager for HIV treatment. Amtabafusp alfa redirects effector T cells by binding to CD3 via a humanized anti-CD3 Fab domain and to HIV envelope proteins via an engineered CD4 domain 1 variant. Amtabafusp alfa exhibits potent, broad-spectrum activity against a variety of HIV isolates and specifically kills HIV-infected cells. Amtabafusp alfa can be used for research on HIV infection .
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Cat. No.: HY-181841
CAS No.: 2796210-93-8
Research Areas:  

Infection

TLR8 agonist 10 is a selective TLR8 agonist with an EC50 of 0.019 μM in humans. TLR8 agonist 10 activates TLR8-mediated signaling pathways. As a latency-reversing agent, TLR8 agonist 10 reactivates latent HIV-1 reservoirs. TLR8 agonist 10 activates innate cytotoxic natural killer cells to target HIV-infected CD4 + T cells. TLR8 agonist 10 is applicable to research related to HIV-1 infection .
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