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Results for "

Hesperetin

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

1

Biochemical Assay Reagents

12

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15337
    Hesperidin
    Maximum Cited Publications
    30 Publications Verification

    Hesperetin 7-rutinoside

    Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite Cancer
    Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .
    Hesperidin
  • HY-N0168
    Hesperetin
    20+ Cited Publications

    p38 MAPK Autophagy Apoptosis Reactive Oxygen Species (ROS) NF-κB Bcl-2 Family Neurological Disease Cancer
    Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .
    Hesperetin
  • HY-N0101
    Neohesperidin
    5+ Cited Publications

    Hesperetin 7-O-neohesperidoside

    β-catenin Wnt Inflammation/Immunology
    Neohesperidin is a flavonoid compound abundant in citrus plants with antioxidant and anti-inflammatory effects. Neohesperidin can upregulate the Wnt/β-catenin signaling pathway, enhance the nuclear translocation of β-catenin and the differentiation of bone marrow stromal cells .
    Neohesperidin
  • HY-N0168A

    TGF-beta/Smad NF-κB Infection Inflammation/Immunology Cancer
    (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .
    (Rac)-Hesperetin
  • HY-125130
    Hesperetin 7-O-glucoside
    1 Publications Verification

    Hes-7-G

    HMG-CoA Reductase (HMGCR) Bacterial Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Hesperetin 7-O-glucoside is a typical flavonoid monoglucoside, which is an anti-inflammatory agent and an antihypertensive with orally active. Hesperetin 7-O-glucoside is a commonly used food adjuvant. Hesperetin 7-O-glucoside inhibits human intestinal maltase and human HMG-CoA reductase with Ki of 1.8 mM and 9.8 μM, respectively. Hesperetin 7-O-glucoside has antibacterial activity and can regulate intestinal flora and metabolic homeostasis in mice .
    Hesperetin 7-O-glucoside
  • HY-15337R

    Hesperetin 7-rutinoside (Standard)

    Reference Standards Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite Cancer
    Hesperidin (Standard) is the analytical standard of Hesperidin. This product is intended for research and analytical applications. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .
    Hesperidin (Standard)
  • HY-N13183

    HDCG

    Others Others
    Hesperetin dihydrochalcone-4′-O-β-D-glucoside is a type of dihydrochalcone compound that has flavor-modulating properties in various natural zero-calorie/low-calorie sweeteners .
    Hesperetin dihydrochalcone-4′-O-β-D-glucoside
  • HY-N0168AS1

    Isotope-Labeled Compounds NF-κB TGF-beta/Smad Neurological Disease Cancer
    (Rac)-Hesperetin- 13C,d3 is the 13C- and deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .
    (Rac)-Hesperetin-13C,d3
  • HY-113216R

    NG,NG-Dimethylarginine (Standard)

    Reference Standards Endogenous Metabolite NO Synthase Cardiovascular Disease Cancer
    Hesperetin (Standard) is the analytical standard of Hesperetin. This product is intended for research and analytical applications. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis.
    Asymmetric dimethylarginine (Standard)
  • HY-N0168S

    p38 MAPK Apoptosis Autophagy Neurological Disease
    Hesperetin-d3 is the deuterium labeled Hesperetin . Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis .
    Hesperetin-d3
  • HY-W510941

    Drug Derivative Others
    Hesperetin dihydrochalcone is a flavonoid derivative with a flavoring activity .
    Hesperetin dihydrochalcone
  • HY-N0168AR

    Reference Standards NF-κB TGF-beta/Smad Neurological Disease Cancer
    (Rac)-Hesperetin (Standard) is the analytical standard of (Rac)-Hesperetin. This product is intended for research and analytical applications. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .
    (Rac)-Hesperetin (Standard)
  • HY-N0168AS

    Isotope-Labeled Compounds NF-κB TGF-beta/Smad Neurological Disease Cancer
    (Rac)-Hesperetin-d3 is the deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .
    (Rac)-Hesperetin-d3
  • HY-N8793

    Others Others
    Hesperetin 5-β-D-glucopyranoside is a flavonoid component, that can be isolated from Prunus davidiana .
    Hesperetin 5-β-D-glucopyranoside
  • HY-W780205

    Biochemical Assay Reagents Others
    (Rac)-Hesperetin 3'-O-β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    (Rac)-Hesperetin 3'-O-β-D-glucuronide
  • HY-N0101R

    Hesperetin 7-O-neohesperidoside (Standard)

    TGF-beta/Smad Reference Standards Inflammation/Immunology
    Neohesperidin (Standard) is the analytical standard of Neohesperidin. This product is intended for research and analytical applications. Neohesperidin is a flavonoid compound found in high amounts in citrus fruits with anti-oxidant and anti-inflammatory effects.
    Neohesperidin (Standard)
  • HY-W778375

    Apoptosis Inflammation/Immunology Cancer
    Hesperetin triacetate is an active compound with anti-inflammatory and anti-tumor activities. Hesperetin triacetate inhibits bovine serum albumin denaturation in vitro. Hesperetin triacetate inhibits carrageenan-induced paw swelling in mice in vivo. Hesperetin triacetate exhibits anti-proliferative activity against breast cancer cells. Hesperetin triacetate induces DNA degradation and apoptosis in breast cancer cells. Hesperetin triacetate can be used in studies related to breast cancer and inflammation .
    Hesperetin triacetate
  • HY-N18016

    Hesperitin-5,7-dimethyl-ether

    Drug Derivative Others
    4'-Hydroxy-5,7,3'-trimethoxyflavanone (Hesperitin-5,7-dimethyl-ether) (Compound 13) is an O-methylated flavanone and a derivative of Hesperetin (HY-N0168) .
    4'-Hydroxy-5,7,3'-trimethoxyflavanone

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