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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
IFN-α receptor
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "IFN-α receptor" in MCE Product Catalog:
120
120 Publications Verification
Synonyms: R848; S28463
Target:
Research Areas:
Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
2
2 Cited Publications
Research Areas:
GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma .
1
1 Cited Publications
Cat. No.: HY-P99300
CAS No.: 1322627-61-1
Synonyms: QGE 031; Anti-IGHE Recombinant Antibody
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-W011890
CAS No.: 38609-97-1
Target:
Research Areas:
Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer .
1
1 Cited Publications
Synonyms: R848-d5; S28463-d5
1
1 Cited Publications
Cat. No.: HY-P72613
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNAR2; IFN-R-2; Prev. IFNABR; Interferon-Alpha/Beta receptor Beta Chain; Interferon Alpha/Beta receptor 2; Human Interferon Alpha/Beta receptor; Type I Interferon receptor 2; IFN-Alpha Binding Protein; Interferon (Alpha, Beta And Omega) receptor 2; Inter
Species:
Human
Source:
HEK293
Cat. No.: HY-P1758
CAS No.: 153840-64-3
Synonyms: IRRP1
Target:
Research Areas:
Cat. No.: HY-148511A
Purity: 90.20%
Synonyms: CMP-001 sodium
Target:
Research Areas:
Vidutolimod sodium is a CpG-A oligodeoxynucleotide. Vidutolimod sodium is a Toll-like receptor 9 (TLR9) agonist, which activates plasmacytoid dendritic cells (pDCs) and triggers interferon alpha (IFNα) release, leading to a cascade of anti-tumor immune effects.
Cat. No.: HY-P1758A
Synonyms: IRRP1 acetate
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Cat. No.: HY-13740R
CAS No.: 144875-48-9
Synonyms: R848 (Standard); S28463 (Standard)
Research Areas:
Resiquimod (Standard) is the analytical standard of Resiquimod. This product is intended for research and analytical applications. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
Cat. No.: HY-117686
CAS No.: 929551-91-7
Target:
Research Areas:
AZ12441970 is a potent and selectiveToll-like receptor 7 (TLR7) agonist, exhibiting pEC50s of 6.8 and 6.6 for human and rat TLR7. AZ12441970 shows efficacy in a mouse allergic airway model with minimal induction of systemic IFN-α. AZ12441970 can be used for allergic airway disease research .
Cat. No.: HY-W011890R
CAS No.: 38609-97-1
Research Areas:
Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer .
Cat. No.: HY-174630
Target:
Research Areas:
Human IL18R1 mRNA encodes the human interleukin 18 receptor 1 (IL18R1) protein, a cytokine receptor that belongs to the interleukin 1 receptor family. IL18R1 is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells.
Cat. No.: HY-118250A
CAS No.: 1325212-97-2
Research Areas:
GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma .
Cat. No.: HY-163670
CAS No.: 3040038-00-1
Target:
Research Areas:
TLR7 agonist 21 (Compound 27B) is a selective agonist for Toll-like receptor 7(TLR7), with an EC50 of 17.53 nM (for human TLR7) and 41.7 nM (for mouse TLR7). TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6, TNF-α, IFN-α1, and IL-4. TLR7 agonist 21 acts as a vaccine adjuvant, increases levels of IgG and IgA, and protects the mouse from influenza virus infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
