4 Results for "

INS-1E β-cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "INS-1E β-cells" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-13529
CAS No.: 1234703-40-2
Purity:  ≥98.0%
Synonyms: LY2608204; SY-004
Target:  

Glucokinase

Research Areas:  

Metabolic Disease

Globalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes .
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Cat. No.: HY-Y0749
CAS No.: 23150-65-4
Synonyms: Dimethyl glutamate hydrochloride
Target:  

iGluR Phosphatase

Dimethyl L-glutamate hydrochloride (Dimethyl glutamate hydrochloride) is a NMDA receptor ligand and a cell membrane-permeable glutamate precursor. Dimethyl L-glutamate hydrochloride binds to NMDA receptors to regulate osteoblast maturation, and promotes osteoblast proliferation, adhesion, extracellular calcium deposition, and alkaline phosphatase activity. Dimethyl L-glutamate hydrochloride replenishes the glutamate pool in insulin-secreting β cells. Dimethyl L-glutamate hydrochloride can be used in research related to bone defects and non-insulin-dependent diabetes mellitus .
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Cat. No.: HY-W037817
CAS No.: 6525-53-7
Synonyms: Dimethyl glutamate
Dimethyl L-glutamate (Dimethyl glutamate) is a NMDA receptor ligand and a cell membrane-permeable glutamate precursor. Dimethyl L-glutamate binds to NMDA receptors to regulate osteoblast maturation, and promotes osteoblast proliferation, adhesion, extracellular calcium deposition, and alkaline phosphatase activity. Dimethyl L-glutamate replenishes the glutamate pool in insulin-secreting β cells. Dimethyl L-glutamate can be used in research related to bone defects and non-insulin-dependent diabetes mellitus .
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Cat. No.: HY-172786
CAS No.: 1984421-81-9
Target:  

Caspase Apoptosis

Research Areas:  

Metabolic Disease

Caspase-3-IN-3 (compound 7) is a caspase 3 inhibitor. Caspase-3-IN-3 increases cellular ATP levels, inhibits caspase-3 activity, decreases nitrite production, suppresses cytokine-induced apoptosis, and restores Glucose (HY-B0389)-stimulated insulin secretion .
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