6 Results for "

Kme readers

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Kme readers" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100832
CAS No.: 1872382-47-2
Purity:  99.50%
Research Areas:  

Cancer

UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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Cat. No.: HY-16510
CAS No.: 1184136-10-4
Research Areas:  

Cancer

UNC926 is a methyl-lysine (Kme) reader domain inhibitor that inhibits L3MBTL1 with an IC50 of 3.9 μM .
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Cat. No.: HY-115531
CAS No.: 1648707-58-7
Purity:  98.84%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

UNC-2170 is a functionally active, fragment-like ligand for 53BP1 (IC50=29 µM; Kd=22 µM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB) .
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Cat. No.: HY-16510A
CAS No.: 1782573-49-2
Research Areas:  

Cancer

UNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor that inhibits L3MBTL1 with an IC50 of 3.9 μM .
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Cat. No.: HY-118897
CAS No.: 2173992-60-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

UNC-2170 maleate is the maleate salt form of UNC-2170 (HY-115531). UNC-2170 maleate is a selective inhibitor for the methyl-lysine binding protein 53BP1, with IC50 of 29 µM and Kd of 22 µM. UNC-2170 maleate shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB) .
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Cat. No.: HY-100832A
CAS No.: 1872382-48-3
Research Areas:  

Cancer

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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