1872382-48-3
Chemical Structure
UNC3866 TFA
- CAS No.: 1872382-48-3
- Formula:C45H67F3N6O10
- Molecular Weight:909.04
IUPAC Name: methyl N2-(4-(tert-butyl)benzoyl)-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serinate 2,2,2-trifluoroacetate
InChIKey: OWTDCNQKWNEIMZ-QVQSGDHTSA-N
SMILES: OC(C(F)(F)F)=O.O=C(C1=CC=C(C=C1)C(C)(C)C)N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(OC)=O)=O)=O)=O)=O)CC2=CC=CC=C2
Biological Activity: UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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UNC3866 TFA | UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel. | |||||||||||||||||||||
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Keywords
