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Lactuca sativa

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By Targets:	ABA Receptor (1) Bacterial (2) Cholinesterase (ChE) (1) Drug Derivative (3) Phosphatase (1) Phytohormone (1) Reference Standards (1) β-glucuronidase (1)
By Research Areas:	Cancer (1) Infection (3) Metabolic Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120161

AS6 3'-Hexylsulfanylabscisic acid	ABA Receptor Phosphatase	Others
AS6 (3'-Hexylsulfanylabscisic acid) is a PYL antagonist with a K_d value of 0.48 μM for Arabidopsis PYL5. AS6 binds to PYL proteins, and its S-hexyl chain blocks PP2C binding via steric hindrance. AS6 alleviates the inhibitory effect of ABA on seed germination in Arabidopsis and lettuce .

HY-N5099

N-Vanillyldecanamide	Others	Metabolic Disease
N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum, significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner .

HY-119609

Ilicicolin C	Bacterial Cholinesterase (ChE) β-glucuronidase	Infection
Ilicicolin C exhibits antibacterial activity against Pseudomonas syringae with IC₅₀ of 28.5 µg/mL. Ilicicolin C exhibits weak inhibitory activities against acetylcholinesterase (AChE) and β-glucuronidase with IC₅₀ of 30-43 µg/mL. Ilicicolin C exhibits weak cytoxicity in human lung fibroblasts with IC₅₀ of 64-120 µg/mL. Ilicicolin C affects seed germination and root tip growth of lettuce .

HY-W748468

6-Isopentenyloxyisobergapten	Drug Derivative Bacterial	Infection
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC₅₀ of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC₅₀ of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .

HY-N13800

3-O-Debenzoylzeylenone	Phytohormone	Infection Cancer
3-O-Debenzoylzeylenone is a polyoxygenated cyclohexene plant growth hormone that exists in the leaves of Uvaria purpurea and the aerial parts of Uvaria grandiflora. 3-O-Debenzoylzeylenone is an auxin analog that inhibits root growth and promotes shoot growth of Lactuca sativa seedlings. 3-O-Debenzoylzeylenone exhibits cytotoxicity against various cancer cells and can be used in studies related to lung cancer, melanoma, epidermoid carcinoma, liver cancer, gastric cancer, colon adenocarcinoma, acute leukemia, breast cancer, and prostate cancer .

HY-N18344

Cichorioside B	Drug Derivative	Others
Cichorioside B (Compound 9) is a sesquiterpene lactone glycoside that can be isolated from Lactuca sativa L var. anagustata .

HY-N11950

N-Vanillyloctanamide	Others	Others
N-Vanillyloctanamide is a capsaicinoid that has the activity of inhibiting the root growth of plant seedlings. N-Vanillyloctanamide significantly reduces the root length of Lactuca sativa (seedling) in a dose-dependent manner .

HY-N5099R

N-Vanillyldecanamide (Standard)	Others Reference Standards	Metabolic Disease
N-Vanillyldecanamide (Standard) is the analytical standard of N-Vanillyldecanamide (HY-N5099). This product is intended for research and analytical applications. N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum, significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner .

HY-N17336

7-Ketostigmasterol	Drug Derivative	Others
7-Ketostigmasterol is a sterol present in the hull of Oryza sativa(rice) .

N-Vanillyldecanamide	Monophenols Capsicum annuum L. Classification of Application Fields Phenols Metabolic Disease Solanaceae Plants Disease Research Fields Source Classification	Others
N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum, significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner .

Ilicicolin C	Structural Classification Microorganisms Antibiotics Source Classification	Bacterial Cholinesterase (ChE) β-glucuronidase
Ilicicolin C exhibits antibacterial activity against Pseudomonas syringae with IC₅₀ of 28.5 µg/mL. Ilicicolin C exhibits weak inhibitory activities against acetylcholinesterase (AChE) and β-glucuronidase with IC₅₀ of 30-43 µg/mL. Ilicicolin C exhibits weak cytoxicity in human lung fibroblasts with IC₅₀ of 64-120 µg/mL. Ilicicolin C affects seed germination and root tip growth of lettuce .

6-Isopentenyloxyisobergapten	Structural Classification Semenovia transiliensis Regel & Herder Apiaceae Coumarins Phenylpropanoids Plants Source Classification	Drug Derivative Bacterial
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC₅₀ of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC₅₀ of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .

3-O-Debenzoylzeylenone	Structural Classification Uvaria grandiflora Roxb. Other Phenylpropanoids Phenylpropanoids Plants Annonaceae Source Classification	Phytohormone
3-O-Debenzoylzeylenone is a polyoxygenated cyclohexene plant growth hormone that exists in the leaves of Uvaria purpurea and the aerial parts of Uvaria grandiflora. 3-O-Debenzoylzeylenone is an auxin analog that inhibits root growth and promotes shoot growth of Lactuca sativa seedlings. 3-O-Debenzoylzeylenone exhibits cytotoxicity against various cancer cells and can be used in studies related to lung cancer, melanoma, epidermoid carcinoma, liver cancer, gastric cancer, colon adenocarcinoma, acute leukemia, breast cancer, and prostate cancer .

Cichorioside B	Structural Classification Terpenoids Sesquiterpenes Asteraceae Lactuca sativa var. angustana Irish Plants Source Classification	Drug Derivative
Cichorioside B (Compound 9) is a sesquiterpene lactone glycoside that can be isolated from Lactuca sativa L var. anagustata .

N-Vanillyloctanamide	Monophenols Capsicum annuum L. Phenols Solanaceae Plants Source Classification	Others
N-Vanillyloctanamide is a capsaicinoid that has the activity of inhibiting the root growth of plant seedlings. N-Vanillyloctanamide significantly reduces the root length of Lactuca sativa (seedling) in a dose-dependent manner .

N-Vanillyldecanamide (Standard)	Structural Classification Monophenols Capsicum annuum L. Phenols Solanaceae Plants Source Classification	Others Reference Standards
N-Vanillyldecanamide (Standard) is the analytical standard of N-Vanillyldecanamide (HY-N5099). This product is intended for research and analytical applications. N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum, significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner .

7-Ketostigmasterol	Triterpenes Structural Classification Terpenoids Gramineae Oryza sativa L. Plants Source Classification	Drug Derivative
7-Ketostigmasterol is a sterol present in the hull of Oryza sativa(rice) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Lactuca sativa

Inhibitors & Agonists

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Natural
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