3,5-Dimethoxybibenzyl

3,5-Dimethoxybibenzyl (compound 5) (0.1-4 mM; 3 days) exhibits weak inhibitory activity on root elongation of Lactuca sativa seedlings, with 77.9% root growth remaining even at the concentration of 4 mM^[1].
3,5-Dimethoxybibenzyl (0.1-10 μg/mL; 5 days) inhibits the attachment of Balanus improvisus nauplii, with an IC₅₀ of 1.0 μg/mL, and shows low toxicity (7.7%) at 5 μg/mL^[1].
3,5-Dimethoxybibenzyl (0.001-20 μg/mL; 5 days) inhibits metamorphosis of Ciona savignyi ascidian larvae via a toxic mode of action, with an IC₅₀ of 3 μg/mL and an IC₉₉ of 21.1 μg/mL^[1].
3,5-Dimethoxybibenzyl (maximum concentration 10 μg/mL; 5 days) exhibits MIC values of 0.1, 0.1, 10, and 10 μg/mL against the attachment of H. coffeaeformis, P. roscoffensis, C. closterium, and P. purpureum, respectively. Its MIC values for inhibiting the growth of the aforementioned microalgae are 0.01, 0.01, 1, and 10 μg/mL, respectively.
3,5-Dimethoxybibenzyl (up to 10 μg/mL; 48 h) potently inhibits the growth of Halomonas aquamarina and Shewanella putrefaciens, with an MIC of 0.01 μg/mL for both, but shows no activity against the other 8 tested marine fouling bacterial strains at concentrations up to 10 μg/mL^[1].

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