21 Results for "

Macrocyclic Antibiotic

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Macrocyclic Antibiotic" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-15739
CAS No.: 66584-72-3
Purity:  ≥98.0%
Synonyms: Antibiotic C 15003P3; Maytansinol isobutyrate
Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
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7
7 Cited Publications
Cat. No.: HY-17580
CAS No.: 873857-62-6
Synonyms: OPT-80; PAR-101
Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research .
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6
6 Cited Publications
Cat. No.: HY-13557
CAS No.: 104987-12-4
Purity:  ≥98.0%
Synonyms: Immunomycin; FR-900520; FK520
Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research .
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5
5 Cited Publications
Cat. No.: HY-17566
CAS No.: 1405-37-4
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease .
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2
2 Cited Publications
Cat. No.: HY-N6686
CAS No.: 21411-53-0
Synonyms: Pristinamycin IIA; Ostreogrycin A
Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by?Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
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Cat. No.: HY-107486
CAS No.: 56377-79-8
Purity:  97.05%
Synonyms: Multhiomycin; RP 9671
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .
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Cat. No.: HY-125728
CAS No.: 67401-56-3
Purity:  ≥99.0%
Target:  

Bacterial Parasite HCV

Research Areas:  

Infection

Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor with an EC50 range of 0.1-0.5 μM . Micrococcin P1 has in vitro antibacterial activity against Gram-positive bacterial strains. The MIC values of Micrococcin P1 against S. aureus 1974149, E. faecalis 1674621 and S. pyogenes 1744264 are 2 μg/mL, 1 μg/mL and 1 μg/mL, respectively . Micrococcin P1 is also a potent inhibitor of the malaria parasite Plasmodium falciparum .
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Cat. No.: HY-P3270
CAS No.: 11003-38-6
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Capreomycin is a macrocyclic peptide antibiotic. Capreomycin can be used for anti-multidrug-resistant-tuberculosis research. Capreomycin can inhibit phenylalanine synthesis in in mycobacterial ribosomes translation
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Cat. No.: HY-107486R
CAS No.: 56377-79-8
Synonyms: Multhiomycin (Standard); RP 9671 (Standard)
Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .
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Cat. No.: HY-13557R
CAS No.: 104987-12-4
Synonyms: Immunomycin (Standard); FR-900520 (Standard); FK520 (Standard)
Ascomycin (Standard) is the analytical standard of Ascomycin. This product is intended for research and analytical applications. Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research[1][2].
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Cat. No.: HY-139105
CAS No.: 72902-38-6
Target:  

Microtubule/Tubulin

Research Areas:  

Infection Cancer

20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic .
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Cat. No.: HY-17580R
CAS No.: 873857-62-6
Synonyms: OPT-80 (Standard); PAR-101 (Standard)
Fidaxomicin (Standard) is the analytical standard of Fidaxomicin. This product is intended for research and analytical applications. Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research .
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Cat. No.: HY-N10585
CAS No.: 2254483-96-8
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .
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Cat. No.: HY-137085
CAS No.: 141443-40-5
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum .
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Cat. No.: HY-137084
CAS No.: 141443-39-2
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum .
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Cat. No.: HY-125512
CAS No.: 158475-33-3
Target:  

Antibiotic

Research Areas:  

Infection

Saccharocarcin B is a macrocyclic lactone antibiotic that is active against the Gram-positive bacteria M. luteus and S. aureus as well as the Gram-negative bacteria C. trachomatis.
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Cat. No.: HY-15739R
CAS No.: 66584-72-3
Synonyms: Antibiotic C 15003P3 (Standard); Maytansinol isobutyrate (Standard)
Ansamitocin P-3 (Standard) is the analytical standard of Ansamitocin P-3. This product is intended for research and analytical applications. Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
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Cat. No.: HY-P10700
CAS No.: 2097285-98-6
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity .
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Cat. No.: HY-N6686R
CAS No.: 21411-53-0
Synonyms: Pristinamycin IIA (Standard); Ostreogrycin A (Standard)
Virginiamycin M1 (Standard) is the analytical standard of Virginiamycin M1. This product is intended for research and analytical applications. Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by?Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) . Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
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Cat. No.: HY-P11676
CAS No.: 1814918-91-6
Synonyms: BRII-693; QPX9003
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Soralimixin (BRII-693), a Polymyxin derivative, is a next-generation intravenous (IV)-administered synthetic macrocyclic peptide antibiotic. Soralimixin can be used for the study of infections caused by drug-resistant Gram-negative pathogens .
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