2097285-98-6
Chemical Structure
RO7196472
- CAS No.: 2097285-98-6
- Formula:C41H49ClN10O3S
- Molecular Weight:797.41
InChIKey: BDHOZQIIBFIAMB-IMKBVMFZSA-N
SMILES: ClC1=C2C(CNC([C@@H](N(C([C@@H](NC([C@@H](NCC3=CC=CN=C3S2)CCCN)=O)CCCCN)=O)C)CC4=CNC5=CC=CC=C45)=O)=C(C6=CN=C(N)C=C6)C=C1
Biological Activity: RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity[1].
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RO7196472 | RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity. | |||||||||||||||||||||
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Keywords