7 Results for "

Multiple myeloma (MM)

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Multiple myeloma (MM)" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-16699
CAS No.: 1403783-31-2
Target:  

HDAC

Research Areas:  

Cancer

Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM) .
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Cat. No.: HY-P99744
CAS No.: 2254522-19-3
Synonyms: TAK-573

Target:  

CD38

Research Areas:  

Inflammation/Immunology Cancer

Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice .
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Cat. No.: HY-144763
CAS No.: 3033267-42-1
Target:  

Apoptosis

Research Areas:  

Cancer

XPO1-IN-1 (compound D4) is an orally active and potent XPO1 inhibitor, with an IC50 of 24 nM in MM.1S cell. XPO1-IN-1 can efficiently induce cell apoptosis and cell cycle arrest. XPO1-IN-1 displays favorable metabolic stability and pharmacokinetic properties. XPO1-IN-1 can be used for multiple myeloma (MM) research .
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Cat. No.: HY-157871
Target:  

MAP3K

Research Areas:  

Cancer

TAK1-IN-5 (Compound 26) is an inhibitor of the transforming growth factor-β activated kinase (TAK1) with an IC50 value of 55 nM. TAK1-IN-5 can inhibit the growth of MPC-11 and H929 cells with a GI50 lower than 30 nM. TAK1-IN-5 can be used in the study of multiple myeloma .
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Cat. No.: HY-149019
CAS No.: 2454133-88-9
Target:  

c-Kit Apoptosis

Research Areas:  

Cancer

Antitumor agent-70 (compound 8b) has anti-tumor activity and can induce cell apoptosis. Antitumor agent-70 inhibits multiple myeloma with an IC50 value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially for c-Kit .
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Cat. No.: HY-169763
CAS No.: 2361297-58-5
Target:  

IRE1 Apoptosis

Research Areas:  

Cancer

D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces Apoptosis. D-F07 has antitumor activity .
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Cat. No.: HY-161840
Target:  

FGFR

Research Areas:  

Cancer

Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM .
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