2361297-58-5
2361297-58-5
Chemical Structure
D-F07
- CAS. Nr.: 2361297-58-5
- Formula:C18H21NO6
- Molecular Weight:347.36
InChIKey: APGGXGRMZQTNTP-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C3=C1CN(CC3)C)C=C(C(O)=C2C4OCCCO4)OC
Biological Activity: D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces Apoptosis. D-F07 has antitumor activity[1][2].
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D-F07 | D-F07 is a prodrug with an aldehyde shielding group and an IRE-1 inhibitor that induces Apoptosis. D-F07 has antitumor activity. | |||||||||||||||||||||
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References
- [1]. Shao A, et al. Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy. Mol Cancer Ther. 2020 Dec;19(12):2432-2444. [Content Brief]
- [2]. Shao A, et al. IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy. Mol Pharm. 2022 Apr 4;19(4):1059-1067. [Content Brief]
