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N-linked glycosylation

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By Targets:	Akt (1) Aminotransferases (Transaminases) (1) Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (1) Exosomes (1) Fungal (1) Glycosidase (1) HIV (3) Influenza Virus (4) mTOR (1) Reference Standards (1) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (5) Infection (4) Inflammation/Immunology (1)

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Peptides

Inhibitory Antibodies

Natural
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0098

Tunicamycin 150+ Cited Publications	Antibiotic Influenza Virus Fungal Bacterial Aminotransferases (Transaminases) Exosomes	Infection Inflammation/Immunology Cancer
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits **N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses** and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .

HY-W009783

1-Deoxymannojirimycin hydrochloride 1 Publications Verification	HIV Influenza Virus	Infection Cancer
1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a **N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1** strains . 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

HY-P2929B

PNGase F (Immobilized, Microspin)	Glycosidase	Others
PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .

HY-W009783A

Deoxymannojirimycin hydrochloride	HIV Influenza Virus	Infection Cancer
Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. Deoxymannojirimycin hydrochloride is also a **N-linked glycosylation inhibitor. Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1** strains . Deoxymannojirimycin hydrochloride increases high mannose structures. Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

HY-P3118

Bz-IEGR-pNA acetate	Biochemical Assay Reagents	Others
Bz-IEGR-pNA acetate is a trypsin substrate that can be hydrolyzed by prostate kinase release enzyme-related peptide KLKs .

HY-W009783R

1-Deoxymannojirimycin hydrochloride (Standard)	Reference Standards HIV Influenza Virus	Infection Cancer
1-Deoxymannojirimycin (hydrochloride) (Standard) is the analytical standard of 1-Deoxymannojirimycin (hydrochloride) (HY-W009783). This product is intended for research and analytical applications. 1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1 strains . 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

HY-P992392

JM1-24-3	Transmembrane Glycoprotein Akt mTOR	Cancer
JM1-24-3 is an anti-MUC18 mouse monoclonal antibody with a K_d value of 1.60e-9 M. JM1-24-3 reduces the phosphorylation levels of p-AKT (Ser473) and p-mTOR (Ser2448) in a time-dependent manner. JM1-24-3 exhibits anticancer activity against melanoma. JM1-24-3 can be used in studies related to metastatic melanoma .

Cat. No.	Product Name	Type

HY-W009783A

Deoxymannojirimycin hydrochloride	Biochemical Assay Reagents
Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. Deoxymannojirimycin hydrochloride is also a **N-linked glycosylation inhibitor. Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1** strains . Deoxymannojirimycin hydrochloride increases high mannose structures. Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

Deoxymannojirimycin hydrochloride

Biochemical Assay Reagents

Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1 strains . Deoxymannojirimycin hydrochloride increases high mannose structures. Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

Bz-IEGR-pNA acetate	Biochemical Assay Reagents	Others
Bz-IEGR-pNA acetate is a trypsin substrate that can be hydrolyzed by prostate kinase release enzyme-related peptide KLKs .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992392

JM1-24-3	Transmembrane Glycoprotein Akt mTOR	Cancer
JM1-24-3 is an anti-MUC18 mouse monoclonal antibody with a K_d value of 1.60e-9 M. JM1-24-3 reduces the phosphorylation levels of p-AKT (Ser473) and p-mTOR (Ser2448) in a time-dependent manner. JM1-24-3 exhibits anticancer activity against melanoma. JM1-24-3 can be used in studies related to metastatic melanoma .

Tunicamycin 150+ Cited Publications	Structural Classification Antifungal Classification of Application Fields Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Antiviral Anticancer Inflammation/Immunology Disease Research Fields Source Classification	Antibiotic Influenza Virus Fungal Bacterial Aminotransferases (Transaminases) Exosomes
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits **N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses** and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .

1-Deoxymannojirimycin hydrochloride 1 Publications Verification	Infection Alkaloids Piperidine Alkaloids other families Classification of Application Fields Plants Disease Research Fields Source Classification	HIV Influenza Virus
1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a **N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1** strains . 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

1-Deoxymannojirimycin hydrochloride (Standard)	Alkaloids Piperidine Alkaloids Structural Classification other families Plants Source Classification	Reference Standards HIV Influenza Virus
1-Deoxymannojirimycin (hydrochloride) (Standard) is the analytical standard of 1-Deoxymannojirimycin (hydrochloride) (HY-W009783). This product is intended for research and analytical applications. 1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1 strains . 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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N-linked glycosylation

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Natural
Products