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NOR

" in MedChemExpress (MCE) Product Catalog:

147

Inhibitors & Agonists

3

Fluorescent Dye

2

Biochemical Assay Reagents

2

Peptides

28

Natural
Products

1

Recombinant Proteins

13

Isotope-Labeled Compounds

4

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108357
    6-Diazo-5-oxo-L-nor-Leucine
    10+ Cited Publications

    L-6-Diazo-5-oxoNORleucine; DON

    Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
    6-Diazo-5-oxo-L-nor-Leucine
  • HY-12053A
    Vinorelbine ditartrate
    Maximum Cited Publications
    21 Publications Verification

    KW-2307; NOR-5'-anhydrovinblastine ditartrate

    Microtubule/Tubulin Autophagy Neurological Disease Cancer
    Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
    Vinorelbine ditartrate
  • HY-13637
    Ganciclovir
    25+ Cited Publications

    BW 759; 2'-NOR-2'-deoxyguanosine

    CMV HSV Antibiotic Nucleoside Antimetabolite/Analog Infection Cancer
    Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
    Ganciclovir
  • HY-112885B
    nor-NOHA monoacetate
    5 Publications Verification

    Nω-Hydroxy-NOR-L-arginine monoacetate

    Arginase Apoptosis Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA monoacetate
  • HY-112885A
    nor-NOHA acetate
    5 Publications Verification

    Nω-Hydroxy-NOR-L-arginine acetate

    Arginase Apoptosis Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA acetate
  • HY-101737
    24-Norursodeoxycholic acid
    1 Publications Verification

    NORucholic acid; NOR-UDCA

    Biochemical Assay Reagents Inflammation/Immunology
    24-norursodeoxycholic acid (Norucholic acid) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties.
    24-Norursodeoxycholic acid
  • HY-100784
    Dihydrokainic acid
    1 Publications Verification

    EAAT Neurological Disease
    Dihydrokainic acid is a glutamate transporters (especially GLT1) inhibitor. Dihydrokainic acid targets GLT1 with high affinity, effectively inhibiting its transport function. Dihydrokainic acid exerts its effect by inhibiting the uptake of glutamate, leading to an increase in extracellular glutamate concentration, thereby affecting neuronal excitability and neurotransmission. Dihydrokainic acid is mainly applied in the field of neuroscience for research on glutamate-related neural functions, epilepsy, learning, and memory .
    Dihydrokainic acid
  • HY-112885C
    nor-NOHA dihydrochloride
    5 Publications Verification

    Nω-Hydroxy-NOR-L-arginine dihydrochloride

    Apoptosis Arginase Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA dihydrochloride
  • HY-18832

    Ephrin Receptor Cancer
    AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf .
    AWL-II-38.3
  • HY-12949
    ML204
    5+ Cited Publications

    TRP Channel Neurological Disease
    ML204 is a potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels .
    ML204
  • HY-117040
    nor-Binaltorphimine
    5+ Cited Publications

    NORbinaltorphimine; NORBNI

    Opioid Receptor Neurological Disease
    nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid receptor. nor-Binaltorphimine blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. nor-Binaltorphimine suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. nor-Binaltorphimine is applicable to research related to neurological disorders such as pain .
    nor-Binaltorphimine
  • HY-100903

    NOR-Binaltorphimine dihydrochloride; NOR-BNI dihydrochloride

    Opioid Receptor Neurological Disease
    Norbinaltorphimine dihydrochloride (nor-Binaltorphimine dihydrochloride; nor-BNI dihydrochloride) is a selective, long-acting competitive antagonist of the κ-opioid receptor. Norbinaltorphimine dihydrochloride blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. Norbinaltorphimine dihydrochloride suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. Norbinaltorphimine dihydrochloride is applicable to research related to neurological disorders such as pain .
    Norbinaltorphimine dihydrochloride
  • HY-112885

    Nω-Hydroxy-NOR-L-arginine

    Apoptosis Arginase Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA is a selective and reversible arginase inhibitor. nor-NOHA induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA has anti-leukemic activity. nor-NOHA can used in study of endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA
  • HY-D1509

    Fluorescent Dye Others
    Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
    Phenazine ethosulfate
  • HY-D1266

    NO-red

    Fluorescent Dye Others
    RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
    RB-OPD
  • HY-139899

    Taste Receptor Others
    S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo .
    S6821
  • HY-126326

    Epoxide Hydrolase Metabolic Disease
    SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH .
    SWE101
  • HY-W742532

    N-Ethyl-NOR-LSD

    5-HT Receptor Dopamine Receptor Neurological Disease
    ETH-LAD (N-Ethyl-nor-LSD) is an activator for 5-HT2A receptor with Ki of 5.1 nM. ETH-LAD exhibits affinity for dopamine receptor D1 and dopamine receptor D2 with Ki of 22.1 nM and 4.4 nM. ETH-LAD acts as psychoactive substance in rat model .
    ETH-LAD
  • HY-W270810

    Nuclear Hormone Receptor 4A/NR4A Cancer
    NR4A agonist-1, a fatty acid mimetic (FAM), is a potent NR4A agonist. NR4A agonist-1 exhibits high agonist potency on NR4A receptors Nurr1, Nur77, and NOR-1, with EC50s of 0.09 μM, 0.04 μM, and 0.15 μM, respectively .
    NR4A agonist-1
  • HY-13637A
    Ganciclovir sodium
    25+ Cited Publications

    BW 759 sodium; 2'-NOR-2'-deoxyguanosine sodium

    CMV HSV Antibiotic Nucleoside Antimetabolite/Analog Infection Cancer
    Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
    Ganciclovir sodium
  • HY-13637R

    BW 759 (Standard); 2'-NOR-2'-deoxyguanosine (Standard)

    Reference Standards CMV HSV Antibiotic Nucleoside Antimetabolite/Analog Infection Cancer
    Ganciclovir (Standard) is the analytical standard of Ganciclovir. This product is intended for research and analytical applications. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
    Ganciclovir (Standard)
  • HY-W722043

    O-456

    Drug Intermediate Dopamine Receptor Neurological Disease
    MFZ 2-13 (O-456) is an N-demethylated intermediate and N-nor-analogue of MFD 2-12. MFZ 2-13 inhibits dopamine uptake through the human dopamine receptor with an IC50 of 1.4 nM .
    MFZ 2-13
  • HY-13637S

    BW 759-d5; 2'-NOR-2'-deoxyguanosine-d5

    Isotope-Labeled Compounds CMV HSV Antibiotic Nucleoside Antimetabolite/Analog Infection
    Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) .
    Ganciclovir-d5
  • HY-W743888

    6-Allyl-6-NOR-LSD

    5-HT Receptor Dopamine Receptor Neurological Disease
    AL-LAD (6-Allyl-6-nor-LSD) is an activator for 5-HT2A receptor with Ki of 3.4-8.1 nM. AL-LAD exhibits affinity for dopamine receptor D1 and dopamine receptor D2 with absolute affinitiesK0.5 of 189 nM and 12.3 nM. AL-LAD acts as psychoactive substance in mouse model .
    AL-LAD
  • HY-N15317

    β-Phocaecholic acid

    Drug Metabolite Metabolic Disease
    Phocaecholic acid (β-Phocaecholic acid) is a bile acid found in duck bile. Phocaecholic acid can be excreted into bile and partially decarboxylated to nor-chenodeoxycholic acid in rats. Phocaecholic acid is promising for research of bile acid metabolism and related diseases .
    Phocaecholic acid
  • HY-12949A
    ML204 hydrochloride
    5+ Cited Publications

    TRP Channel Neurological Disease
    ML204 hydrochloride is a novel, potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels .
    ML204 hydrochloride
  • HY-N10851

    Others Others
    23-Nor-6-oxopristimerol is a phenolic dinor-triterpene .
    23-Nor-6-oxopristimerol
  • HY-179004

    VU6022856

    Potassium Channel Neurological Disease
    ONO-9517601 is a potent, orally active, selective and CNS penetrant dual TREK-1/TREK-2 inhibitor (TREK-1 IC50= 0.067 μM, TREK-2 IC50= 0.23 μM). ONO-9517601 displays robust efficacy in an MK-801 (HY-15084B) challenge rat novel object recognition (NOR) paradigm. ONO-9517601 can be used for research on neurological and cognitive disorders .
    ONO-9517601
  • HY-114861

    Opioid Receptor Neurological Disease
    Nor-6α-Oxycodol is structurally similar to known opioids and is a metabolite of Oxycodone .
    Nor-6α-Oxycodol
  • HY-43711

    mAChR Neurological Disease
    Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity .
    Nor-benzetimide
  • HY-131896

    NOR4

    NO Synthase Cardiovascular Disease
    FR144420 (NOR4) is an orally active nitric oxide (NO)-releasing agent with vasodilatory and antiplatelet effects. FR144420 induces cGMP-mediated vasodilation and inhibits platelet aggregation. FR144420 is promising for research of cardiovascular diseases, particularly angina pectoris and coronary artery spasm .
    FR144420
  • HY-108357R

    L-6-Diazo-5-oxoNORleucine (Standard); DON (Standard)

    Reference Standards Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-B0132B

    MK-0366 (nicotinate)

    Bacterial Antibiotic Infection
    Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration .
    Norfloxacin (nicotinate)
  • HY-13637B

    BW-759 hydrate; 2'-NOR-2'-deoxyguanosine hydrate

    CMV HSV Antibiotic Nucleoside Antimetabolite/Analog Infection Cancer
    Ganciclovir (BW 759) hydrate, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir hydrate also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir hydrate inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir hydrate has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
    Ganciclovir hydrate
  • HY-179005

    VU6024391

    Potassium Channel Neurological Disease
    ONO-7927846 is a potent, orally active, selective and CNS penetrant dual TREK-1/TREK-2 inhibitor (TREK-1 IC50= 0.11 μM, TREK-2 IC50= 0.29 μM). ONO-7927846 displays robust efficacy in an MK-801 (HY-15084B) challenge rat novel object recognition (NOR) paradigm. ONO-7927846 can be used for research on neurological and cognitive disorders .
    ONO-7927846
  • HY-12053AS
    Vinorelbine-d3 ditartrate
    2 Publications Verification

    KW-2307-d3 ditartrate; NOR-5'-anhydrovinblastine-d3 ditartrate

    Microtubule/Tubulin Autophagy Cancer
    Vinorelbine-d3 (ditartrate) is the deuterium labeled Vinorelbine ditartrate. Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
    Vinorelbine-d3 ditartrate
  • HY-149812

    Bacterial Parasite Infection
    Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
    AcrB-IN-4
  • HY-170047

    11-NOR-9β-carboxy-HHC

    Cannabinoid Receptor Neurological Disease
    11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9β-carboxy-HHC) is structurally similar to known phytocannabinoids .
    11-Nor-9(R)-carboxy-hexahydrocannabinol
  • HY-170047A

    11-NOR-9α-carboxy-HHC

    Cannabinoid Receptor Neurological Disease
    11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9α-carboxy-HHC) is structurally similar to known phytocannabinoids .
    11-Nor-9(S)-carboxy-hexahydrocannabinol
  • HY-172080

    Cannabinoid Receptor Neurological Disease
    (-)-7-Nor-7-carboxy cannabidiol is a phytocannabinoid metabolite. (-)-7-Nor-7-carboxy cannabidiol is a metabolite of Cannabidiol.
    (-)-7-Nor-7-carboxy cannabidiol
  • HY-131101R

    Reference Standards Phosphodiesterase (PDE) Others
    Nor-Acetildenafil (Standard) is the analytical standard of Nor-Acetildenafil. This product is intended for research and analytical applications. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor .
    Nor-Acetildenafil (Standard)
  • HY-143542S

    Isotope-Labeled Compounds Others
    Nor neostigmine-d6 is the deuterium labeled Nor neostigmine .
    Nor neostigmine-d6
  • HY-132435S

    Isotope-Labeled Compounds Others
    Nor Propranolol-d7 hydrochloride is the deuterium labeled Nor Propranolol hydrochloride .
    Nor Propranolol-d7 hydrochloride
  • HY-157061S

    Isotope-Labeled Compounds Others
    7-Nor-7-carboxycannabidiol-d10 is deuterium-labeled 7-Nor-7-carboxycannabidiol .
    7-Nor-7-carboxycannabidiol-d10
  • HY-19407

    PPAR Others
    Nor-LY-510929 is a compound whose development in the field of endocrinology and metabolism was stopped in 2005. Its specific active mechanism and application details are not described in detail based on the existing information.
    Nor-LY-510929
  • HY-146067

    Fungal Reactive Oxygen Species (ROS) Infection
    β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity .
    β-Nor-lapachone
  • HY-N15709

    Bacterial Infection
    Nor-Rubrofusarin gentiobioside is a phenolic glycoside de-rubrofusarin that can be isolated from the seeds of Cassia tora. The same series of extracts of Nor-Rubrofusarin gentiobioside have antibacterial effects on Staphylococcus aureus strains .
    Nor-Rubrofusarin gentiobioside
  • HY-168793

    Cannabinoid Receptor Neurological Disease
    (±)-9-Nor-9β-hydroxy Hexahydrocannabinol is structurally similar to known synthetic cannabinoids.
    (±)-9-Nor-9β-hydroxy Hexahydrocannabinol
  • HY-N1713

    Others Neurological Disease
    29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM .
    29-Nor-20-oxolupeol
  • HY-131101

    Phosphodiesterase (PDE) Others
    Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor .
    Nor-Acetildenafil

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