9 Results for "

PI3kδ inhibitor 1

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "PI3kδ inhibitor 1" in MCE Product Catalog:

Cat. No.: HY-15288
CAS No.: 1332075-63-4
Target:  

PI3K

Research Areas:  

Cancer

PI3kδ inhibitor 1 is a potent and selective PI3Kδ inhibitor with an IC50 of 3.8 nM.
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Cat. No.: HY-10549
CAS No.: 1172118-03-4
Target:  

PI3K

Research Areas:  

Cancer

PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM.
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Cat. No.: HY-162713
CAS No.: 2791417-66-6
Target:  

EGFR PI3K PPAR

Research Areas:  

Cancer

MTX-531 is an oral drug that inhibits EGFR (with an IC50 of 14.7 nM) and PI3K (with IC50 values of 6.4, 233, 8.3, and 1.1 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ respectively), and it has anti-tumor effects. MTX-531 also acts as a weak agonist of PPARγ, with an IC50 of 2.5 µM, helping to alleviate hyperglycemia induced by PI3K inhibitors .
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Cat. No.: HY-60298
CAS No.: 79762-54-2
Research Areas:  

Others

6-Bromo-1H-indazole is an indazole derivative that serves as an intermediate for research related to organic synthesis. 6-Bromo-1H-indazole acts as a building block for the preparation of PI3Kδ inhibitors, and also functions as a synthetic intermediate for the preparation of colchicine site-targeted tubulin polymerization inhibitors[1][2].
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Cat. No.: HY-112614
CAS No.: 2135639-94-8
Target:  

ATM/ATR

Research Areas:  

Cancer

ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibitor, with an IC50 of 0.7 nM, shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM). ATM Inhibitor-1 exhibits anti-tumor activity .
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Cat. No.: HY-W040417
CAS No.: 155905-77-4
Target:  

PI3K

Research Areas:  

Others

Boc-L-cyclobutylglycine is a Boc-protected L-cyclic amino acid and synthetic intermediate in the preparation of purinyl quinazolinone PI3Kδ inhibitors .
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Cat. No.: HY-112602
CAS No.: 1949802-49-6
Target:  

PI3K mTOR

Research Areas:  

Cancer

PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively . Antitumor activity .
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Cat. No.: HY-112439
CAS No.: 2242109-74-4
Target:  

PI3K

Research Areas:  

Inflammation/Immunology Cancer

PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM .
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Cat. No.: HY-40029
CAS No.: 625471-18-3
Synonyms: (S)-(+)-3-Amino-1-boc-PIperidine
(S)-1-Boc-3-aminopiperidine is a key intermediate for the synthesis of various novel inhibitors, such as CHK1 inhibitors and PI3Kδ inhibitors .
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