PI3Kγ inhibitor 1
PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM.
For research use only. We do not sell to patients.
- CAS No.: 1172118-03-4
- Formula: C32H26N8O2S
- Molecular Weight:586.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI3Kδ 100 nM (IC50) |
PI3Kγ 100 nM (IC50) |
PI3Kα 10 μM (IC50) |
PI3Kβ 10 μM (IC50) |
In Table 3, PI3Kγ inhibitor 1 (Compound 168) inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively. PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1172118-03-4
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Molecular Weight 586.67
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Formula C32H26N8O2S
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SMILES
O=C1N(C2=CC=CC=C2C)C(CN3N=C(C4=CC=C(N=C(NC(C)=O)S5)C5=C4)C6=C3N=CN=C6N)=CC7=CC=CC(C)=C71
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PI3Kγ inhibitor 1 Related Classifications
HY-10549 Related Classifications
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