Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
PROTAC SMARCA2 degrader-32
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "PROTAC SMARCA2 degrader-32" in MCE Product Catalog:
Cat. No.: HY-170343
CAS No.: 3033586-50-1
Target:
Research Areas:
PROTAC SMARCA2 degrader-32 is a potent, selective SMARCA2 PROTAC degrader, with DC50 values of 1.3 nM and 94 nM against SMARCA2 and SMARCA4, respectively. PROTAC SMARCA2 degrader-32 exhibits IC50 against SMARCA2, SMARCA4 and the VHL E3 ubiquitin ligase of 30 nM, 63 nM and 25 nM, respectively. PROTAC SMARCA2 degrader-32 inhibits the growth of SMARCA4-deficient cancer cells. It can be used in research on cancers such as fibrosarcoma .
Cat. No.: HY-159459
CAS No.: 2568273-79-8
Target:
Research Areas:
PROTAC SMARCA2/4 degrader-32 is a SMARCA2/SMARCA4 PROTAC degrader. PROTAC SMARCA2/4 degrader-32 induces ubiquitination, proteasome-mediated degradation, and recruits the E3 ubiquitin ligase complex. PROTAC SMARCA2/4 degrader-32 can be used in cancer-related research .
Cat. No.: HY-170349
CAS No.: 3033592-44-5
Research Areas:
SMARCA2 ligand-11 is the ligand for SMARCA2, and can be used for synthesis of PROTAC SMARCA2 degrader-32 (HY-170343) as ligand for target protein .
Cat. No.: HY-170348
CAS No.: 2958620-43-2
Target:
Research Areas:
(S)-(S,R,S,R)-AHPC-Me-N3 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-32 (HY-170343) and can be used in the synthesis of PROTACs .
Cat. No.: HY-W560922
CAS No.: 82516-17-4
Target:
Research Areas:
Piperazine-Ac-OMe is a PROTAC linker. Piperazine-Ac-OMe can be used in the synthesis of PROTAC SMARCA2/4-degrader-32 (HY-159459) .
Cat. No.: HY-170352
Research Areas:
E3 Ligase Ligand-linker Conjugate 150 is the conjugate of the ligand for E3 ligase VHL and the linker, that can be used for synthesis of PROTAC SMARCA2 degrader-32 (HY-170343) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
