20 Results for "

Phosphorylase kinase

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "Phosphorylase kinase" in MCE Product Catalog:

Cat. No.: HY-P2757
CAS No.: 9001-88-1
Synonyms: PhK
Target:  

Others

Research Areas:  

Others

Phosphorylase kinase relies on Ca 2+ to exert its activity. Phosphorylase kinase’s sensitivity to Ca 2+ is influenced by its activation state and pH. Phosphorylase kinase can be activated by adrenaline .
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235
235 Publications Verification
Cat. No.: HY-15141
CAS No.: 62996-74-1
Purity:  99.52%
Synonyms: Antibiotic AM-2282; STS; AM-2282
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
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27
27 Cited Publications
Cat. No.: HY-N6732
CAS No.: 99533-80-9
Synonyms: SF2370; Antibiotic K 252a; Antibiotic SF 2370
K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca 2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .
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13
13 Cited Publications
Cat. No.: HY-15424
CAS No.: 24386-93-4
Purity:  99.64%
Synonyms: NSC 113939; 5-ITu
Target:  

Adenosine Kinase

Research Areas:  

Cancer

5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
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2
2 Cited Publications
Cat. No.: HY-P1821
CAS No.: 126768-94-3
Synonyms: MHP4-14
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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2
2 Cited Publications
Cat. No.: HY-P1821A
Synonyms: MHP4-14 TFA
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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1
1 Cited Publications
Cat. No.: HY-P1597
CAS No.: 86555-35-3
Target:  

PKA PKC

Research Areas:  

Cancer

Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide is also an efficient substrate for PKC with a Km of 16 μM .
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1
1 Cited Publications
Cat. No.: HY-P7710
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALM1; Epididymis Secretory Protein Li 72; Prev. CALML2; Calmodulin-3; DD132; CAMIII; PHKD1; CPVT4; CAMI; LQT14; PHKD; CALM3; Calmodulin 1 (Phosphorylase kinase, Delta); CALM2; Phosphorylase kinase Subunit Delta 1; CAM2; Phosphorylase kinase Subunit Delta; CAM3; Prepro-Calmodulin 1; CAMB; Calmodulin-1; CAMC; Calmodulin 3 (Phosphorylase kinase, Delta), Isoform CRA_b; CAM1; Calmodulin 1 (Phosphorylase kinase, Delta), Isoform CRA_a; CALM; EF-Hand Calcium-Binding Domain-Containing Protein 11; CaM; CDNA FLJ61744, Highly Similar To Calmodulin; CAM; Phosphorylase kinase, Delta Subunit; Calmodulin 1; Calmodulin-2
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-E70373
CAS No.: 401941-75-1
Research Areas:  

Others

λ Protein phosphatase is a serine/threonine phosphatase encoded by bacteriophage Lambda. λ Protein phosphatase is activated with requirement for divalent cations, such as Mn 2+. λ Protein phosphatase is able to dephosphorylate casein, adenovirus E1A protein, and the α subunit of phosphorylase kinase
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Cat. No.: HY-15141R
CAS No.: 62996-74-1
Synonyms: Antibiotic AM-2282 (Standard); STS (Standard); AM-2282 (Standard)
Staurosporine (Standard) is the analytical standard of Staurosporine. This product is intended for research and analytical applications. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer[1][2][3][4][5].
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Cat. No.: HY-15424R
CAS No.: 24386-93-4
Synonyms: NSC 113939 (Standard); 5-ITu (Standard)
Research Areas:  

Cancer

5-Iodotubercidin (Standard) is the analytical standard of 5-Iodotubercidin. This product is intended for research and analytical applications. 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
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Cat. No.: HY-P2734
CAS No.: 9032-10-4
Target:  

Phosphatase

Research Areas:  

Others

Phosphorylase a, rabbit muscle is glycogen phosphorylase isolated from rabbit muscle. Phosphorylase a, rabbit muscle catalyzes glycogenolysis, converting glycogen and inorganic phosphate into glucose-1-phosphate to supply energy for muscle contraction .
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Cat. No.: HY-P1873
CAS No.: 150829-21-3
Target:  

Ser/Thr Protease

Research Areas:  

Endocrinology

Phosphorylase Kinase β-Subunit Fragment (420-436) is the β-Subunit fragment (peptide 430-436) of phosphorylase kinase. Phosphorylase kinase is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen .
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Cat. No.: HY-P1873B
Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

Phosphorylase Kinase β-Subunit Fragment (420-436) acetate is the β-Subunit fragment (peptide 430-436) of phosphorylase kinase. Phosphorylase kinase is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen .
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Cat. No.: HY-P1597A
Target:  

PKA PKC

Research Areas:  

Cancer

Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide TFA is also an efficient substrate for PKC with a Km of 16 μM .
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Cat. No.: HY-P75461
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALM2; LP7057 Protein; Calmodulin 2; Calmodulin-1; PHKD2; Calmodulin-3; CAMII; CALML2; PHKD; CAMIII; Calmodulin 2 (Phosphorylase kinase, Delta); LQT15; Phosphorylase kinase Subunit Delta 2; CALM3; Phosphorylase kinase Subunit Delta; CALM1; Prepro-Calmodul
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-E72093
Research Areas:  

Others

[Acetyl-CoA carboxylase] Kinase (EC 2.7.11.27) phosphorylates and inactivates EC 6.4.1.2, acetyl-CoA carboxylase, which can be dephosphorylated and reactivated by EC 3.1.3.17, [phosphorylase] phosphatase.
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Cat. No.: HY-P705595
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NEK3; Phosphorylase B kinase kinase; NIMA Related kinase 3; NimA-Related Protein kinase 3; Never In Mitosis A-Related kinase 3; Hydroxyalkyl-Protein kinase; HSPK36; Glycogen Synthase A kinase; NIMA (Never In Mitosis Gene A)-Related kinase 3; MGC29949; Ser
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-111926R
CAS No.: 81921-35-9
Research Areas:  

Metabolic Disease

N6-Methyladenosine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of N6-Methyladenosine 5'-monophosphate (disodium salt) (HY-111926). This product is intended for research and analytical applications. N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM . N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate Kinase II inhibitor .
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Cat. No.: HY-L044
593 compounds

Nucleoside and nucleotide analogues are synthetic, chemically modified compounds that have been developed to mimic their physiological counterparts in order to exploit cellular metabolism and subsequently be incorporated into DNA and RNA to inhibit cellular division and viral replication. In addition to their incorporation into nucleic acids, nucleoside and nucleotide analogues can interact with and inhibit essential enzymes such as human and viral polymerases (that is, DNA-dependent DNA polymerases, RNA-dependent DNA polymerases or RNA-dependent RNA polymerases), kinases, ribonucleotide reductase, DNA methyltransferases, purine and pyrimidine nucleoside phosphorylase and thymidylate synthase. These actions of nucleoside and nucleotide analogues have potential therapeutic benefits — for example, in the inhibition of cancer cell growth, the inhibition of viral replication as well as other indications.

MCE offers a unique collection of 593 nucleotide compounds including nucleotide, nucleoside and their structural analogues. MCE Nucleotide Compound Library is a useful tool to discover anti-cancer and antiviral drugs for high throughput screening (HTS) and high content screening (HCS).

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