101 Results for "

Photodynamic Therapy

" in MedChemExpress (MCE) Product Catalog:
Products (101)

101 Results for "Photodynamic Therapy" in MCE Product Catalog:

286
286 Publications Verification
Cat. No.: HY-B0146
CAS No.: 129497-78-5
Synonyms: CL 318952
Research Areas:  

Cancer

Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .
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20
20 Cited Publications
Cat. No.: HY-N0305
CAS No.: 5451-09-2
Synonyms: 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
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20
20 Cited Publications
Cat. No.: HY-W854659
CAS No.: 72984-36-2
Synonyms: Ce6 trisodium
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .
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12
12 Cited Publications
Cat. No.: HY-16488
CAS No.: 122341-38-2
Synonyms: m-THPC; KW2345
Research Areas:  

Cancer

Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
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4
4 Cited Publications
Cat. No.: HY-128973
CAS No.: 24533-72-0
Purity:  ≥98.0%
Research Areas:  

Cancer

Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .
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4
4 Cited Publications
Cat. No.: HY-16477
CAS No.: 220201-34-3
Synonyms: ME2906; Mono-L-aspartyl chlorin e6; NPe6
Target:  

Photosensitizer

Research Areas:  

Cancer

Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
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3
3 Cited Publications
Cat. No.: HY-134990
CAS No.: 148471-91-4
Purity:  ≥95.0%
Target:  

Apoptosis

Research Areas:  

Cancer

Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma .
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3
3 Cited Publications
Cat. No.: HY-13722
CAS No.: 149402-51-7
Purity:  99.74%
Synonyms: Photochlor
Research Areas:  

Cancer

HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.
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2
2 Cited Publications
Cat. No.: HY-128972
CAS No.: 25465-77-4
Purity:  ≥95.0%
Research Areas:  

Others

Purpurin 18, a derivative of chlorophyll and a type of dihydroporphyrin, is used to produce photosensitizers. Purpurin 18 photodynamic therapy can induce cell apoptosis and has anti-tumor activity .
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2
2 Cited Publications
Cat. No.: HY-N2575
CAS No.: 77029-83-5
Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml) .
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2
2 Cited Publications
Cat. No.: HY-137473
CAS No.: 6453-67-4
Purity:  99.14%
Synonyms: Pyropheophorbide-a methyl ester
Target:  

Apoptosis

Research Areas:  

Cancer

Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
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1
1 Cited Publications
Cat. No.: HY-D0988
CAS No.: 11016-17-4
Synonyms: R-PE
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
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1
1 Cited Publications
Cat. No.: HY-113011
CAS No.: 1109-28-0
Purity:  ≥98.0%
Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer .
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1
1 Cited Publications
Cat. No.: HY-17644
CAS No.: 1224104-08-8
Synonyms: LUZ11; F2BMet
Research Areas:  

Cancer

Redaporfin (LUZ11) acts as a potent photosensitizer. Redaporfin causes direct antineoplastic effects as well as indirect immune-dependent destruction of malignant lesions .
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1
1 Cited Publications
Cat. No.: HY-A0169A
CAS No.: 79416-27-6
Research Areas:  

Cancer

Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
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1
1 Cited Publications
Cat. No.: HY-N1453
CAS No.: 123940-54-5
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities .
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1
1 Cited Publications
Cat. No.: HY-137475
CAS No.: 35038-32-5
Purity:  99.81%
Research Areas:  

Cancer

Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) .
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1
1 Cited Publications
Cat. No.: HY-111959
CAS No.: 16724-03-1
Purity:  98.90%
Research Areas:  

Endocrinology

2-Selenouracil is a useful specialized photosensitizer for photodynamical therapy .
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Cat. No.: HY-19204
CAS No.: 14320-04-8
Synonyms: ZnPc
Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications .
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Cat. No.: HY-P2213
CAS No.: 109053-09-0
Target:  

MMP Apoptosis

Research Areas:  

Cancer

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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