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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Plasmodium aspartic protease
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Plasmodium aspartic protease" in MCE Product Catalog:
Cat. No.: HY-155130
CAS No.: 3033682-50-4
Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor .
Cat. No.: HY-P5344
Synonyms: Fluorigenic PEXEL peptide
Cat. No.: HY-189251
CAS No.: 1038291-78-9
Target:
Research Areas:
PMV-IN-1 is a plasmepsin V (PMV) inhibitor with an IC50 of 22 μM against Plasmodium vivax PMV. PMV-IN-1 reversibly and non-covalently inhibits Plasmodium aspartic proteases without causing time-dependent inactivation or covalent adduct formation. PMV-IN-1 can be used for research on malaria .
Cat. No.: HY-187367
Target:
Research Areas:
WJM590 is an orally active antimalarial agent that also exhibits inhibitory activities against renin, cathepsin D, BACE1, and plasmodial aspartic proteases. WJM590 inhibits substrate and protein maturation processing mediated by key proteases of Plasmodium falciparum, arrests asexual blood-stage parasites at the late schizont stage, inhibits merozoite release, and blocks malaria parasite transmission via vectors. WJM590 exerts selective inhibitory activity against multiple Plasmodium species and drug-resistant Plasmodium falciparum strains, and reduces parasitemia in infected mice. WJM590 can be used in malaria-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
