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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
Prostaglandin A2
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "Prostaglandin A2" in MCE Product Catalog:
Synonyms: PGA2; Medullin
Prostaglandin A2 (PGA2) is a Cyclopentenone prostaglandin. Prostaglandin A2 induces Caspase-dependent Apoptosis, activates p53. Prostaglandin A2 activates ERK2 and JNK1/SAPK. Prostaglandin A2 shows antiviral activity against HSV-1. Prostaglandin A2 has anti-tumor effects. Prostaglandin A2 can be used for the research of colorectal cancer, colorectal carcinoma, breast carcinoma, and herpetic keratitis .
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Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Thromboxane B2 is a biological inactive product and circulating catabolite of thromboxane A2. Thromboxane B2 levels in peripheral venous blood and coronary sinus blood can be used as a diagnostic marker for angina. Thromboxane B2 level in serum is also associated with inhibition of COX-1 activity inhibition in platelets. Thromboxane B2 is a major product of prostaglandin endoperoxide metabolism. Thromboxane B2 produces dose-related decreases in airflow rate, tidal volume and dynamic lung compliance, whilst simultaneously increasing pulmonary airway resistance in dog model. Thromboxane B2 appears to be a naturally occurring bronchoactive metabolite in the bioconversion of arachidonic acid .
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Ifetroban (BMS-180291) is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .
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1 Cited Publications
Synonyms: BMS-180291 sodium
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Ifetroban (BMS-180291) sodium is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban sodium shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban sodium can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .
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1 Cited Publications
Cat. No.: HY-P4406
CAS No.: 100307-95-7
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1 Cited Publications
Cat. No.: HY-10419A
CAS No.: 81496-19-7
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AH23848 hemicalcium salt is an orally active, selective competitive blocker of the thromboxane A2 receptor, with an IC50 value of 50 nM. AH23848 hemicalcium salt shows no activity against other prostaglandin, serotonin (5-HT) or adenosine diphosphate (ADP) receptors. AH23848 hemicalcium salt can be used in the research of occlusive vascular diseases .
Cat. No.: HY-A0221
CAS No.: 110140-89-1
Synonyms: R 68070
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Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities .
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L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
Cat. No.: HY-118772
CAS No.: 38315-51-4
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17-Phenyl trinor prostaglandin A2 is a synthetic prostaglandin analog .
Synonyms: TM30089 Racemate
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CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist, with a Ki of 0.6 nM for hCRTH2, selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). CAY10471 Racemate also has effect on mouse and rat orthologs of CRTH2 .
Cat. No.: HY-118728
CAS No.: 31753-19-2
Synonyms: PGA2 methyl ester
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Prostaglandin A2 methyl ester (PGA2 methyl ester) is a methylated derivative of the prostaglandin PGA2 (HY-113041) .
Cat. No.: HY-131729
CAS No.: 51639-10-2
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16-Phenoxy tetranor Prostaglandin A2 is a metabolite of uprostone and an analog of the antifertility hormone PGF2α .
Cat. No.: HY-118055
CAS No.: 112839-31-3
Synonyms: 15d-PGA2
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15-Deoxy-Δ12,14-prostaglandin A2 is a synthetic analog of PGA2 .
Cat. No.: HY-114892
CAS No.: 474391-66-7
Synonyms: 8-iso Prostaglandin A2
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15-A2t-Isoprostane (8-iso Prostaglandin A2) is an isoprostaglandin produced by the non-enzymatic oxidation of arachidonic acid .
Cat. No.: HY-165073
CAS No.: 96440-68-5
Synonyms: 15(R)-15-Methyl PGA2
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15(R)-15-Methyl prostaglandin A2 is a biochemical reagent.
Cat. No.: HY-113461
CAS No.: 74872-89-2
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13,14-Dihydro-15-keto-prostaglandin A2 is a product of the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2. It is further broken down into bicyclo PGE2, which acts as a biomarker for PGE2 synthesis .
Cat. No.: HY-172817
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Prostaglandin A2 ethyl ester is an ethyl ester derivative of Prostaglandin A2 (HY-113041). Prostaglandin A2 ethyl ester exhibits vasodilatory activity and has a protective effect on the kidneys .
Cat. No.: HY-124428
CAS No.: 524699-72-7
Synonyms: FK881
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ASP6537 is a potent and selective rhCOX-1 inhibitor with an IC50 of 0.703 nM. ASP6537 has the potential for cardiovascular disease research .
Cat. No.: HY-P4406A
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AZ-1355 is an orally active and effctive lipid-lowering agent. AZ-1355 inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
