6 Results for "

Protein Kinase R (PKR)

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Protein Kinase R (PKR)" in MCE Product Catalog:

  • Targets Recommended:
67
67 Cited Publications
Cat. No.: HY-13820
CAS No.: 1337532-29-2
Purity:  99.66%
Target:  

PERK Autophagy Apoptosis

Research Areas:  

Cancer

GSK2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM.
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2
2 Cited Publications
Cat. No.: HY-P80847
Synonyms: PRKAR2A; PKR2; PRKAR2; cAMP-dependent Protein Kinase type II-alpha regulatory subunit

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat, Pig

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Cat. No.: HY-118131
CAS No.: 1314594-23-4
Purity:  99.79%
Target:  

Pyruvate Kinase

Research Areas:  

Others

PKR-IN-C51 is an ATP-competitive protein kinase R (PKR) inhibitor with a human IC50 of 9 μM and a human Ki of 3.4 μM. PKR-IN-C51 blocks the activation of PKR, inhibits intracellular PKR activation in primary mouse macrophages, and shows no obvious cytotoxicity. PKR-IN-C51 can be used in studies related to the regulation of PKR-mediated signaling pathways .
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Cat. No.: HY-178898
CAS No.: 13072-74-7
7-Oxogedunin (Compound 7DG; Compound 16) is a small molecule that protects macrophages from cell pyroptosis induced by anthrax lethal toxin (LT). Its target is protein kinase R (PKR). 7-Oxogedunin can widely inhibit the assembly of various inflammasomes (NLRP1 and NLRP3) and the activation of caspase-1 by inhibiting the kinase-independent function of PKR. 7-Oxogedunin has growth inhibitory activity on European corn borer larvae. 7-Oxogedunin can be used for LT toxicity inhibition and pest control research .
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Cat. No.: HY-13820R
CAS No.: 1337532-29-2
Research Areas:  

Cancer

GSK2656157 (Standard) is the analytical standard of GSK2656157 (HY-13820). This product is intended for research and analytical applications. GSK2656157 is a selective and ATP-competitive inhibitor of protein Kinase R (PKR)-like endoplasmic reticulum Kinase (PERK) with an IC50 of 0.9 nM.
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Cat. No.: HY-P80283
Synonyms: PKR, PRKR, EIF2AK2, Eukaryotic translation initiation factor 2-alpha Kinase 2, Interferon-inducible RNA-dependent Protein Kinase, P1/eIF-2A Protein Kinase, Protein Kinase RNA-activated, Tyrosine-Protein Kinase EIF2AK2, p68 Kinase, eIF-2A Protein Kinase 2, Protein Kinase R

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP

Reactivity:  

Human

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