1337532-29-2
1337532-29-2
Chemical Structure
GSK2656157
- CAS No.: 1337532-29-2
- Formula:C23H21FN6O
- Molecular Weight:416.45
IUPAC Name: 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethan-1-one
InChIKey: PRWSIEBRGXYXAJ-UHFFFAOYSA-N
SMILES: CC1=CC=CC(CC(N2CCC3=C2C=CC(C4=CN(C)C5=NC=NC(N)=C54)=C3F)=O)=N1
Biological Activity: GSK2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK2656157 | 99.66% | GSK2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM. | ||||||||||||||||||||
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GSK2656157 (Standard) | ≥98% | GSK2656157 (Standard) is the analytical standard of GSK2656157 (HY-13820). This product is intended for research and analytical applications. GSK2656157 is a selective and ATP-competitive inhibitor of protein Kinase R (PKR)-like endoplasmic reticulum Kinase (PERK) with an IC50 of 0.9 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-153160PERK-IN-6 -
Similarity Score 0.67
HY-135220PERK-IN-2 -
Similarity Score 0.66
HY-18072GSK2606414 -
Similarity Score 0.64
HY-137813PERK-IN-4 -
Similarity Score 0.60
HY-119933RIPK1-IN-7 -
Similarity Score 0.56
HY-179235RIPK1-IN-37 -
Similarity Score 0.55
HY-130643PERK-IN-3 -
Similarity Score 0.51
HY-122909GSK2593074A -
Similarity Score 0.49
HY-147575Axl-IN-8 -
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