678 Results for "

Substance

" in MedChemExpress (MCE) Product Catalog:
Products (678)

678 Results for "Substance" in MCE Product Catalog:

349
Dimethyl sulfoxide, meets analytical specification of Ch.P.
Dimethyl sulfoxide, meets analytical specification of Ch.P.
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349 Publications Verification
Cat. No.: HY-Y0320
CAS No.: 67-68-5
Synonyms: DMSO, meets analytical specification of Ch.P.
Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.
106
Methyl-β-cyclodextrin
Methyl-β-cyclodextrin
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106 Cited Publications
Cat. No.: HY-101461
CAS No.: 128446-36-6
Purity:  99.95%
Synonyms: Methyl-beta-cyclodextrin
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
77
Methotrexate hydrate
Methotrexate hydrate
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77 Cited Publications
Cat. No.: HY-14519B
CAS No.: 133073-73-1
Purity:  98.41%
Synonyms: Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate
Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases. It works by inhibiting the process by which cells synthesize DNA.
56
Prostaglandin E2
Prostaglandin E2
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56 Cited Publications
Cat. No.: HY-101952
CAS No.: 363-24-6
Purity:  99.74%
Synonyms: PGE2; Dinoprostone
Category:  

Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Organoid Prostaglandin Receptor Endogenous Metabolite

Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
56
Prostaglandin E2 (Standard)
Prostaglandin E2 (Standard)
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56 Cited Publications
Cat. No.: HY-101952R
CAS No.: 363-24-6
Synonyms: PGE2(Standard); Dinoprostone (Standard)
Category:  

Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Reference Standards Prostaglandin Receptor Endogenous Metabolite

Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
34
PEG400
PEG400
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34 Cited Publications
Cat. No.: HY-Y0873A
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 400
PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
34
Dimethyl sulfoxide
Dimethyl sulfoxide
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34 Cited Publications
Cat. No.: HY-Y0320C
CAS No.: 67-68-5
Synonyms: DMSO
Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.
32
Substance P
Substance P
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32 Cited Publications
Cat. No.: HY-P0201
CAS No.: 33507-63-0
Synonyms: Neurokinin P
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Neurokinin Receptor Endogenous Metabolite

Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
32
Substance P TFA
Substance P TFA
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32 Cited Publications
Cat. No.: HY-P0201A
CAS No.: 148470-19-3
Synonyms: Neurokinin P TFA
Target:  

Neurokinin Receptor Endogenous Metabolite

Research Areas:  

Neurological Disease Metabolic Disease Cancer

Substance P TFA (Neurokinin P TFA) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
10
Mevalonic acid lithium salt
Mevalonic acid lithium salt
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10 Cited Publications
Cat. No.: HY-113071A
CAS No.: 2618458-93-6
Purity:  ≥98.0%
Synonyms: MVA lithium salt
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
9
Taurochenodeoxycholic acid sodium
Taurochenodeoxycholic acid sodium
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9 Cited Publications
Cat. No.: HY-N1429
CAS No.: 6009-98-9
Synonyms: 12-Deoxycholyltaurine sodium
Category:  

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Apoptosis Endogenous Metabolite

Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties .
9
Taurochenodeoxycholic acid
Taurochenodeoxycholic acid
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9 Cited Publications
Cat. No.: HY-N2027
CAS No.: 516-35-8
Synonyms: 12-Deoxycholyltaurine
Category:  

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Caspase Apoptosis Endogenous Metabolite

Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties .
8
Hypericin
Hypericin
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8 Cited Publications
Cat. No.: HY-N0453
CAS No.: 548-04-9
Category:  

Quinones Anthraquinones Guttiferae Hyperlcurn perforatum L. Plants Disease Research Fields Cancer

Target:  

Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase

Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .
8
Hypericin (Standard)
Hypericin (Standard)
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8 Cited Publications
Cat. No.: HY-N0453R
CAS No.: 548-04-9
Category:  

Natural Products Guttiferae Hyperlcurn perforatum L. Phenols Plants Disease Research Fields Cancer

Target:  

Reference Standards Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase

Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .
7
Quinine hemisulfate hydrate
Quinine hemisulfate hydrate
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7 Cited Publications
Cat. No.: HY-D0143B
CAS No.: 207671-44-1
Category:  

Infection Alkaloids Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields

Target:  

Parasite Potassium Channel Dengue Virus Flavivirus

Quinine hemisulfate hydrate is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine hemisulfate hydrate acts as a potassium channel inhibitor that suppresses the +100 mV current of MT mSlo3 (KCa5.1) channels induced by voltage pulses, with an IC50 value of 169 μM. Quinine hemisulfate hydrate serves as a fluorescence standard reference substance with fluorescence spectrum calibration and validation activity .
6
Brilliant Blue FCF
Brilliant Blue FCF
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6 Cited Publications
Cat. No.: HY-D0915
CAS No.: 3844-45-9
Synonyms: Acid Blue 9; FD&C Blue No. 1; E133
Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm.
5
Cortodoxone
Cortodoxone
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5 Cited Publications
Cat. No.: HY-77839
CAS No.: 152-58-9
Synonyms: 11-Deoxycortisol; cortexolone; Reichstein's Substance S
Category:  

Endogenous metabolite Disease Research Fields Endocrinology Steroids

Target:  

Glucocorticoid Receptor Endogenous Metabolite

Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
5
Xylose
Xylose
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5 Cited Publications
Cat. No.: HY-N0537
CAS No.: 58-86-6
Synonyms: D-(+)-Xylose; (+)-Xylose; Wood sugar
Category:  

Other Diseases Endogenous metabolite Disease Research Fields Saccharides Monosaccharides

Target:  

Environmental Pollutants Endogenous Metabolite

Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .
4
Netupitant
Netupitant
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4 Cited Publications
Cat. No.: HY-16346
CAS No.: 290297-26-6
Synonyms: CID 6451149
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology Cancer

Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK1) receptor antagonist with a Ki of 0.95 nM for hNK1 in CHO cells. Netupitant has antiemetic affect .
4
Paradol
Paradol
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4 Cited Publications
Cat. No.: HY-14617
CAS No.: 27113-22-0
Purity:  99.87%
Synonyms: [6]-Gingerone; [6]-Paradol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

COX

Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.
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