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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
T. gondii
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "T. gondii" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: BRL 6231 free base
Research Areas:
WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine< (HY-18062)-resistant P. falciparum strains) as well as T. gondii .
6
6 Publications Verification
Synonyms: BRL 6231
Research Areas:
WR99210 hydrochloride is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 hydrochloride shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains as well as T. gondii .
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
3
3 Cited Publications
Target:
Research Areas:
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease .
3
3 Cited Publications
Research Areas:
LHVS is a potent, non-selective, irreversible, cell-permeable cysteine protease and cathepsin inhibitor. LHVS decreases actin ring formation. LHVS inhibits T. gondii invasion with an IC50 of 10 μM .
3
3 Cited Publications
Cat. No.: HY-W013100
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Research Areas:
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
Category:
Natural Products Plants Eupatorium buniifolium Hook. & Arn. Cytokinin Agricultural Research Umbelliferae Phytohormone Disease Research Fields Inflammation/Immunology Cancer
Target:
Target:
Research Areas:
Fluphenazine decanoate is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
Cat. No.: HY-125818S3
Purity: 99.0%
Synonyms: Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9 dilithium
Cat. No.: HY-W013100R
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium (Standard); 5'-CTP disodium (Standard)
Target:
Reference Standards DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Research Areas:
Cytidine-5'-triphosphate (Cytidine triphosphate) (Standard) disodium is the analytical standard of Cytidine-5'-triphosphate disodium (HY-W013100). This product is intended for research and analytical applications. Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
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Research Areas:
Fluphenazine decanoate dihydrochloride is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
Cat. No.: HY-116039
CAS No.: 73090-70-7
Synonyms: Ro11-8958
Research Areas:
Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor. Epiroprim displays excellent activity against staphylococci, enterococci, pneumococci, and streptococci .
Cat. No.: HY-118621
CAS No.: 126062-19-9
JCP174 is an inhibitor of palmitoyl protein thioesterase-1 (TgPPT1), a depalmitoylase in the parasite T. gondii . JCP174 is also an inhibitor of porcine pancreatic elastase and human leukocyte elastase .
Cat. No.: HY-114909
CAS No.: 331839-29-3
TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1，thereby causing a decrease in the activity of the parasite's myosin motor .
Cat. No.: HY-175246
CAS No.: 294197-66-3
Antitoxoplasmal agent-1 (Compound 4) is an antiparasitic agent. Antitoxoplasmal agent-1 has strong activity and selectivity against T. gondii, with an IC50 of 3.1 μM. Antitoxoplasmal agent-1 also has certain activity against L. major amastigotes, with an EC50 of 23.3 μM. Antitoxoplasmal agent-1 can be used in the research of parasite-related diseases .
Cat. No.: HY-115972
CAS No.: 2863602-85-9
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Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC50 = 0.51 µM) and INC-5 epimastigote form (IC50 = 3.06 µM), posseses anti-T. gondii activity .
Cat. No.: HY-128398
CAS No.: 1236038-23-5
CpCDPK1/TgCDPK1-IN-2 (Compound 7r) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 12 and 5 nM, respectively. CpCDPK1/TgCDPK1-IN-2 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection .
Cat. No.: HY-128399
CAS No.: 1092788-87-8
CpCDPK1/TgCDPK1-IN-3 (Compound 20) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 0.003 and 0.0036 µM, respectively. CpCDPK1/TgCDPK1-IN-3 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection .
Cat. No.: HY-125818C
CAS No.: 652154-13-7
Synonyms: Cytidine triphosphate disodium hydrate; 5'-CTP disodium hydrate
Research Areas:
Cytidine 5′-triphosphate is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
