1 Result for "

TPC-1 human papillary thyroid carcinoma cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TPC-1 human papillary thyroid carcinoma cells" in MCE Product Catalog:

Cat. No.: HY-183783
Target:  

PROTACs RET STAT ERK Apoptosis

Research Areas:  

Endocrinology Cancer

PROTAC RET Degrader 2 is a RET degrader with a target IC50 of 0.36 nM. PROTAC RET Degrader 2 is mainly composed of RET-IN-34 (HY-183729) and Thalidomide (HY-14658). PROTAC RET Degrader 2 mediates RET degradation via the ubiquitin-proteasome system. PROTAC RET Degrader 2 induces apoptosis, inhibits colony-forming ability, and exhibits antiproliferative activity in cancer cells. PROTAC RET Degrader 2 suppresses tumor growth in xenograft models. PROTAC RET Degrader 2 can be used in research related to medullary thyroid carcinoma, papillary thyroid carcinoma, and RET fusion-positive lung adenocarcinoma .
loading...
    loading...