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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Tubocurarine
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Tubocurarine" in MCE Product Catalog:
1
1 Cited Publications
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Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the α-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc .
Category:
Alkaloids Other Diseases Phenols Polyphenols Plants Cissampelos pareira Disease Research Fields Isoquinoline Alkaloids Menispermaceae
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Cat. No.: HY-124047
CAS No.: 40709-76-0
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RX 67668 is a potent cholinesterase inhibitor with an IC50 of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue .
Cat. No.: HY-118504S
Cat. No.: HY-N6609B
CAS No.: 75413-87-5
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Cat. No.: HY-188047
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AS3580239 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3580239 promotes acetylcholine (ACh) signaling via m-nAChR, causing a leftward shift of the ACh concentration-response curve. AS3580239 enhances electrically stimulated isometric contraction of the extensor digitorum longus (EDL) muscle. AS3580239 improves neurotransmission and enhances muscle strength. AS3580239 can be used for research on myasthenia gravis .
Cat. No.: HY-188046
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Research Areas:
AS3566987 is a positive allosteric modulator of the skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3566987 promotes acetylcholine signaling via the skeletal muscle-type nicotinic acetylcholine receptor, and receptor activation requires the involvement of acetylcholine. AS3566987 can be used in the research of neuromuscular diseases (including myasthenia gravis and congenital myasthenic syndrome) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
