47 Results for "

active constituent

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "active constituent" in MCE Product Catalog:

9
Stachydrine hydrochloride
Stachydrine hydrochloride
0 Images
9 Publications Verification
Cat. No.: HY-N0738
CAS No.: 4136-37-2
Category:  

Alkaloids Erythrophleum fordii Oliv. Pyrrole Alkaloids Labiatae Plants Disease Research Fields Cancer

Target:  

NF-κB Endogenous Metabolite

Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases . Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities .
loading...
    loading...
View All Sizes
7
Narirutin
Narirutin
0 Images
7 Cited Publications
Cat. No.: HY-N0804
CAS No.: 14259-46-2
Category:  

Flavonoids Flavonones Rutaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Citrus

Target:  

Bacterial

Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
loading...
    loading...
View All Sizes
5
Mogroside V
Mogroside V
0 Images
5 Cited Publications
Cat. No.: HY-N0502
CAS No.: 88901-36-4
Category:  

Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research

Target:  

Reactive Oxygen Species (ROS)

Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
loading...
    loading...
View All Sizes
4
Irisflorentin
Irisflorentin
0 Images
4 Cited Publications
Cat. No.: HY-N0268
CAS No.: 41743-73-1
Category:  

Iridaceae Flavonoids Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

NO Synthase

Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
loading...
    loading...
View All Sizes
2
Schisandrol B
Schisandrol B
0 Images
2 Cited Publications
Cat. No.: HY-N0692
CAS No.: 58546-54-6
Synonyms: Gomisin-A; TJN-101; Wuweizi alcohol-B
Category:  

Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

Reactive Oxygen Species (ROS) Cytochrome P450 Autophagy

Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities .
loading...
    loading...
View All Sizes
2
(-)-Cedrene
(-)-Cedrene
0 Images
2 Cited Publications
Cat. No.: HY-135190
CAS No.: 469-61-4
Purity:  ≥98.0%
Synonyms: α-cedrene
Category:  

Infection Cedrus deodara (Roxburgh) G. Don Pinaceae Terpenoids Sesquiterpenes Metabolic Disease Plants Disease Research Fields

Target:  

Environmental Pollutants Bacterial

(-)-Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-)-Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-)-Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL). (-)-Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL). (-)-Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-)-Cedrene exhibits anti-obesity activity .
loading...
    loading...
View All Sizes
2
4-Methoxycinnamaldehyde
4-Methoxycinnamaldehyde
0 Images
2 Cited Publications
Cat. No.: HY-W013605A
CAS No.: 1963-36-6
Synonyms: p-Methoxycinnamaldehyde
Category:  

Infection Araceae Ketones, Aldehydes, Acids Acorus gramineus Soland. Plants Disease Research Fields

Target:  

Environmental Pollutants RSV

4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC50 of 0.055 μg/mL .
loading...
    loading...
View All Sizes
1
Isoscopoletin
Isoscopoletin
0 Images
1 Cited Publications
Cat. No.: HY-N1365
CAS No.: 776-86-3
Synonyms: 6-Hydroxy-7-methoxycoumarin
Category:  

Coumarins Plants Compositae Infection other families Monophenols Phenols Phenylpropanoids Disease Research Fields Sindora sumatrana Miq. Cancer

Target:  

HBV p38 MAPK NF-κB STAT Akt ERK JNK

Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively . Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication . Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-κB/STAT/AKT signaling pathway .
loading...
    loading...
View All Sizes
1
Pyrethrin II
Pyrethrin II
0 Images
1 Cited Publications
Cat. No.: HY-108170
CAS No.: 121-29-9
Purity:  31.27%
Category:  

Lycium barbarum L. Natural Products Other Diseases Plants Solanaceae Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

Insecticide Environmental Pollutants Parasite

Pyrethrin II is an orally active insecticidal ester of chrysanthemum acid found in Chrysanthemum cinerariifolium and C. coccineum Willd., an active constituent of pyrethrum extract with low mammalian toxicity. Pyrethrin II exhibits antiparasitic activity. Pyrethrin II can be used for the research of allergic contact dermatitis and parasitic infections .
loading...
    loading...
View All Sizes
1
Narirutin (Standard)
Narirutin (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-N0804R
CAS No.: 14259-46-2
Category:  

Flavonoids Flavonones Rutaceae Phenols Polyphenols Plants Citrus

Target:  

Reference Standards Bacterial

Narirutin (Standard) is the analytical standard of Narirutin. This product is intended for research and analytical applications. Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
loading...
    loading...
View All Sizes
trans-Urocanic acid
trans-Urocanic acid
0 Images
Cat. No.: HY-113008B
CAS No.: 3465-72-3
Purity:  99.60%
Synonyms: (E)-Urocanic acid; trans-UCA
Category:  

Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function .
loading...
    loading...
View All Sizes
Umbellulone
Umbellulone
0 Images
Cat. No.: HY-135013
CAS No.: 546-78-1
Purity:  99.60%
Category:  

Other Monoterpenes Terpenoids Myrtaceae Plants Myrtus communis L.

Target:  

TRP Channel

Umbellulone is an active constituent of the leaves of Umbellularia californica. Umbellulone stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism .
loading...
    loading...
View All Sizes
Methyl linoleate
Methyl linoleate
0 Images
Cat. No.: HY-N1481
CAS No.: 112-63-0
Category:  

other families Metabolic Disease Lipids Plants Disease Research Fields

Target:  

Environmental Pollutants Tyrosinase

Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins .
loading...
    loading...
View All Sizes
Ethyl cinnamate
Ethyl cinnamate
0 Images
Cat. No.: HY-Y0121
CAS No.: 103-36-6
Category:  

Kaempferia galanga L. Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields Zingiberaceae

Target:  

Environmental Pollutants Apoptosis Parasite VEGFR

Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
loading...
    loading...
View All Sizes
Fenamic acid
Fenamic acid
0 Images
Cat. No.: HY-W040265
CAS No.: 91-40-7
Synonyms: N-Phenylanthranilic acid
Target:  

Chloride Channel

Research Areas:  

Inflammation/Immunology

Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent - .
loading...
    loading...
View All Sizes
Tanshinone IIB
Tanshinone IIB
0 Images
Cat. No.: HY-N1179
CAS No.: 17397-93-2
Category:  

Cardiovascular Disease Quinones Neurological Disease Labiatae Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones

Target:  

Apoptosis

Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis .
loading...
    loading...
View All Sizes
12-O-Methylcarnosic acid
12-O-Methylcarnosic acid
0 Images
Cat. No.: HY-N7510
CAS No.: 62201-71-2
Synonyms: 12-Methoxycarnosic acid
Category:  

Paramacrolobium coeruleum (Taub.) J.Léonard Cylicodiscus gabunensis Harms Plants Infection Monophenols Labiatae Terpenoids Phenols Diterpenoids Disease Research Fields Cancer

Target:  

5 alpha Reductase

12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity .
loading...
    loading...
View All Sizes
Tetramethylammonium iodide
Tetramethylammonium iodide
0 Images
Cat. No.: HY-W014861
CAS No.: 75-58-1
Synonyms: Tetramethyl-ammoniuiodide
Tetramethylammonium iodide (Tetramethyl-ammoniuiodide) is a capillary active agent and weakly capillary active quasi-simple salt. Tetramethylammonium iodide decreases aqueous solution surface tension with increasing concentration and exhibits surface accumulation of constituent ions at liquid-vapor interfaces .
loading...
    loading...
View All Sizes
Isoscopoletin (Standard)
Isoscopoletin (Standard)
0 Images
Cat. No.: HY-N1365R
CAS No.: 776-86-3
Synonyms: 6-Hydroxy-7-methoxycoumarin (Standard)
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants Compositae Sindora sumatrana Miq.

Target:  

Reference Standards HBV p38 MAPK NF-κB STAT Akt ERK JNK

Isoscopoletin (Standard) is the analytical standard of Isoscopoletin. This product is intended for research and analytical applications. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively . Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication . Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-κB/STAT/AKT signaling pathway .
loading...
    loading...
View All Sizes
Platycoside M1
Platycoside M1
0 Images
Cat. No.: HY-N8810
CAS No.: 917482-67-8
Target:  

Others

Research Areas:  

Others

Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
loading...
    loading...
View All Sizes
Assay Types