4136-37-2
Chemical Structure
Stachydrine hydrochloride
- CAS No.: 4136-37-2
- Formula:C7H14ClNO2
- Molecular Weight:179.64
IUPAC Name: (S)-2-carboxy-1,1-dimethylpyrrolidin-1-ium chloride
InChIKey: DUNMULOWUUIQIL-RGMNGODLSA-N
SMILES: C[N+]1(CCC[C@H]1C([O-])=O)C.Cl
Biological Activity: Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases[2]. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities[1].
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Stachydrine hydrochloride | 99.90% | Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities. | ||||||||||||||||||||
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- [1]. Guo W, et al. Effect of Leonurus Stachydrine on myocardial cell hypertrophy. Zhong Yao Cai. 2012 Jun;35(6):940-3. [Content Brief]
- [2]. Wang M, et al. Stachydrine hydrochloride inhibits proliferation and induces apoptosis of breast cancer cells via inhibition of Akt and ERK pathways. Am J Transl Res. 2017 Apr 15;9(4):1834-1844. [Content Brief]
Keywords