1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. trans-Urocanic acid

trans-Urocanic acid (Synonyms: (E)-Urocanic acid; trans-UCA)

Cat. No.: HY-113008B
Handling Instructions

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.

For research use only. We do not sell to patients.

trans-Urocanic acid Chemical Structure

trans-Urocanic acid Chemical Structure

CAS No. : 3465-72-3

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Description

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

trans-urocanic acid (trans-UCA) partially inhibits cytotoxic function of IL-2-activated NK cells and reduces IL-2-induced activation of NK cells[1].
trans-urocanic acid (trans-UCA;100 μg/mL) slightly decreases cell proliferation and viability of primary human keratinocytes[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[2]

Cell Line: Primary human keratinocytes
Concentration: 100 μg/mL
Incubation Time: 24 hours
Result: Decreased cell proliferation and viability.
Molecular Weight

138.12

Formula

C₆H₆N₂O₂

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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trans-Urocanic acid
Cat. No.:
HY-113008B
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